Abstract
Introduction
High body mass index (BMI) and wound drainage following total joint arthroplasty (TJA) can lead to wound healing complications and periprosthetic joint infection. Silver-embedded occlusive dressings and negative pressure wound therapy (NPWT) have been shown to reduce these complications. The purpose of this prospective trial was to compare the effect of silver-embedded dressings and NPWT on wound complications in patients with BMI ≥ 35 m/kg2 undergoing TJA.
Methods
We conducted a randomized control trial of patients who had a BMI > 35 m/kg2 and were undergoing primary TJA between October 2017 and February 2020. Patients who underwent revision surgery, or those with an active infection, previous scar, history of wound healing complications, post-traumatic degenerative joint disease with hardware, or inflammatory arthritis were excluded. Patients were randomized to receive either a silver-embedded occlusive dressing (control) or NPWT. Frequency distributions, means, and standard deviations were used to describe patient demographics, postoperative complications, 90-day readmissions, and reoperations. T-test and chi-squared tests were used to test for significant differences between continuous and categorical variables, respectively.
Results
Two hundred-thirty patients with 3-month follow-up were included. One-hundred-fifteen patients received the control and 115 patients received NPWT. There were six patients (5.2%) in the control group with wound complications (drainage: n = 5, non-healing wound: n = 1) and two patients (1.7%) in the NPWT with complications (drainage: n = 2). There were no 90-day readmissions in the control group versus two (1.8%) 90-day readmissions in the NPWT group. Finally, three patients (2.6%) in the control group underwent reoperations (irrigation and debridement [I&D], I&D with modular implant exchange, and implant revision), while none in the NPWT group had undergone reoperation. The two groups showed insignificant differences in wound complications (p = 0.28), 90-day readmissions (p = 0.50), and reoperations (p = 0.25).
Conclusion
Patients with BMI ≥ 35 m/kg2 undergoing TJA have no statistical difference in early wound complications, readmissions, or reoperations when treated with either silver-embedded dressings or NPWT.
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Change history
12 November 2022
A Correction to this paper has been published: https://doi.org/10.1007/s00402-022-04691-z
17 July 2022
A Correction to this paper has been published: https://doi.org/10.1007/s00402-022-04552-9
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Authors 1, 2, 3, and 4 have no conflict of interests to disclose. Author 5 owns stock or stock options in Intellijoint, Gauss surgical, and PSI. Author 5 is a paid consultant for Smith & Nephew and Intellijoint. Author 5 is also on the editorial/governing board for the Journal of Arthroplasty and Arthroplasty Today and is a board member for AAOS and AAHKS. Author 6 is a paid consultant/speaker for Convatec, DePuy, Pacira, Think Surgical, and TJO. Author 6 has received royalties from Elsevier and OrthoDevelopment. Author 6 is also on the editorial/governing board of the Journal of Arthroplasty and is a board member for AAOS.
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The study was conducted according to the guidelines of the Declaration of Helsinki, and approved by the Institutional Review Board of NYU School of Medicine (study number: i17-00496_CR2).
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Lygrisse, K.A., Teo, G., Singh, V. et al. Comparison of silver-embedded occlusive dressings and negative pressure wound therapy following total joint arthroplasty in high BMI patients: a randomized controlled trial. Arch Orthop Trauma Surg 143, 2989–2995 (2023). https://doi.org/10.1007/s00402-022-04530-1
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DOI: https://doi.org/10.1007/s00402-022-04530-1