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Comparison of proprioception between osteoarthritic and age-matched unaffected knees: a systematic review and meta-analysis

  • Orthopaedic Surgery
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Archives of Orthopaedic and Trauma Surgery Aims and scope Submit manuscript

Abstract

Purpose

Theoretically, proprioceptive acuity could decrease in patients with knee osteoarthritis. However, there have been conflicting results in terms of proprioceptive deficit in osteoarthritic knees. The purpose of this systematic review and meta-analysis was to compare knee proprioception between osteoarthritic and healthy control knees.

Methods

Studies comparing proprioception in osteoarthritic and healthy knees of age-matched control group using thresholds to detect passive motion (TTDPM) or joint position sense (JPS) tests were identified. JPS was assessed by measuring the reproduction of passive positioning (RPP) or active positioning (RAP) of the knees.

Results

Seventeen studies were finally included in this meta-analysis. The pooled results of the analyses of the TTDPM for both 30° and 45° knee flexion showed that the mean angle of error was 0.83° greater (95% confidence interval: 0.44 to 1.23°; p < 0.001) in the osteoarthritic knees than in control knees. The pooled data of the RAP and RPP also showed that the mean angle of error was 1.89° greater in the osteoarthritic knees than in the control group. The mean difference in the angle of error between the osteoarthritic knees and control group was 1.06° greater in the JPS test than in the TTDPM (p < 0.001).

Conclusion

The knee proprioceptive acuity of the patients with knee osteoarthritis was poorer than that of the patients with unaffected knees in the age-matched control group both in terms of the TTDPM and JPS; clinical relevance of these deficits needs to be clarified in further studies.

Level of evidence

Meta-analysis, Level II.

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Acknowledgements

We are very grateful for the helpful comments provided by the reviewers and journal editors. No benefits in any form have been received or will be received from a commercial party related directly or indirectly to the subject of this article, nor have any funds been received in support of this study.

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This study has no funding support.

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Author notes

  1. Sung-Sahn Lee and Hyun-Jung Kim contributed equally to the work.

Authors and Affiliations

  1. Department of Orthopaedic Surgery, Ilsan Paik Hospital, Inje University School of Medicine, Goyangsi, Gyeonggido, Korea

    Sung-Sahn Lee

  2. Department of Preventive Medicine, Korea University College of Medicine, Seoul, Korea

    Hyun-Jung Kim

  3. Department of Orthopaedic Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, Korea

    Donghee Ye & Dae-Hee Lee

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  1. Sung-Sahn Lee
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Correspondence to Dae-Hee Lee.

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Lee, SS., Kim, HJ., Ye, D. et al. Comparison of proprioception between osteoarthritic and age-matched unaffected knees: a systematic review and meta-analysis. Arch Orthop Trauma Surg 141, 355–365 (2021). https://doi.org/10.1007/s00402-020-03418-2

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  • DOI: https://doi.org/10.1007/s00402-020-03418-2

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