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Total knee arthroplasty in patients with skeletal dysplasia

  • Knee Arthroplasty
  • Published:
Archives of Orthopaedic and Trauma Surgery Aims and scope Submit manuscript

Abstract

Introduction

Dwarfism is a challenge in arthroplasty. The anatomical features provide a lot of pitfalls. The aim of this study was to follow-up growth-restricted patients after endoprosthetic treatment.

Materials and methods

138 knee arthroplasties in patients with a height ≤150 cm between January 1, 2000 and May 5, 2013 at our institution were enrolled in this study. 124 cases were available for 1-year follow-up. Out of these, 43 cases were available for 5-year follow-up so far. 14 patients were lost to follow-up.

Results

IKS score increased from 35 ± 16 on admission to 67 ± 22 (p < 0.001) at 1-year follow-up and 65 ± 23 (p < 0.001) at 5-year follow-up. Function Score increased from 40 ± 29 on admission to 64 ± 21 (p < 0.001) at 1-year follow-up and 63 ± 23 (p < 0.001) at 5-year follow-up. Revision surgery was required in one case (0.8 %) after 1-year follow-up, and in an additional three cases (7 %) after 5-year follow-up.

Conclusions

Knee arthroplasty can be performed in patients suffering from dwarfism with good clinical benefits. However, survival rates are worse compared to the general population.

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References

  1. Laing P (2014) Growth failure and hormone therapy. J Wound Care 23(4):S3–S9

    Google Scholar 

  2. Anjum A, Afzal MF, Iqbal SM, Sultan MA, Hanif A (2014) Congenital hypothyroidism in neonates. Indian J Endocrinol Metab 18(2):213–216. doi:10.4103/2230-8210.129114

    Article  PubMed Central  PubMed  Google Scholar 

  3. Ranke MB (2013) Treatment of children and adolescents with idiopathic short stature. Nat Rev Endocrinol 9(6):325–334. doi:10.1038/nrendo.2013.71

    Article  CAS  PubMed  Google Scholar 

  4. Laederich MB, Horton WA (2010) Achondroplasia: pathogenesis and implications for future treatment. Curr Opin Pediatr 22(4):516–523. doi:10.1097/MOP.0b013e32833b7a69

    Article  PubMed  Google Scholar 

  5. Tomatsu S, Montano AM, Oikawa H, Smith M, Barrera L, Chinen Y, Thacker MM, Mackenzie WG, Suzuki Y, Orii T (2011) Mucopolysaccharidosis type IVA (Morquio A disease): clinical review and current treatment. Curr Pharm Biotechnol 12(6):931–945. doi:10.2174/138920111795542615

    Article  CAS  PubMed  Google Scholar 

  6. Cormier-Daire V (2008) Spondylo-epi-metaphyseal dysplasia. Best Pract Res Clin Rheumatol 22(1):33–44. doi:10.1016/j.berh.2007.12.009

    Article  CAS  PubMed  Google Scholar 

  7. Stanescu R, Stanescu V, Muriel MP, Maroteaux P (1993) Multiple epiphyseal dysplasia, Fairbank type: morphologic and biochemical study of cartilage. Am J Med Genet 45(4):501–507. doi:10.1002/ajmg.1320450420

    Article  CAS  PubMed  Google Scholar 

  8. Osagie L, Figgie M, Bostrom M (2012) Custom total hip arthroplasty in skeletal dysplasia. Int Orthop 36(3):527–531. doi:10.1007/s00264-011-1314-7

    Article  PubMed Central  PubMed  Google Scholar 

  9. Ain MC, Shirley ED, Pirouzmanesh A, Skolasky RL, Leet AI (2006) Genu varum in achondroplasia. J Pediatr Orthop 26(3):375–379. doi:10.1097/01.bpo.0000203013.04272.b6

    Article  PubMed  Google Scholar 

  10. Lee ST, Song HR, Mahajan R, Makwana V, Suh SW, Lee SH (2007) Development of genu varum in achondroplasia: relation to fibular overgrowth. J Bone Joint Surg Br 89(1):57–61. doi:10.1302/0301-620X.89B1.18223

    Article  CAS  PubMed  Google Scholar 

  11. Koudela K Jr, Koudela K Sr, Koudelova J (2011) Total knee arthroplasty in severe valgus deformity in a patient with achondroplasia. Acta Chir Orthop Traumatol Cech 78(6):578–582

    PubMed  Google Scholar 

  12. de Waal Malefijt MC, van Kampen A, van Gemund JJ (2000) Total knee arthroplasty in patients with inherited dwarfism—a report of five knee replacements in two patients with Morquio’s disease type A and one with spondylo-epiphyseal dysplasia. Arch Orthop Trauma Surg 120(3–4):179–182

    Article  PubMed  Google Scholar 

  13. Feibel JB, Steensen RN (2002) Bilateral total knee arthroplasty in an achondroplastic dwarf 43 years after bilateral tibial osteotomies. J Knee Surg 15(1):39–40

    PubMed  Google Scholar 

  14. Heisel J, Hesselschwerdt HJ (1996) Endoprosthetic joint replacement in Morquio-Brailsford syndrome. Z Orthop Ihre Grenzgeb 134(2):189–194. doi:10.1055/s-2008-1039794

    Article  CAS  PubMed  Google Scholar 

  15. Slupik A, Bialoszewski D (2007) Comparative analysis of clinical usefulness of the Staffelstein Score and the Hospital for Special Surgery Knee Score (HSS) for evaluation of early results of total knee arthroplasties, Preliminary report. Ortop Traumatol Rehabil 9(6):627–635

    PubMed  Google Scholar 

  16. Insall JN, Dorr LD, Scott RD, Scott WN (1989) Rationale of the Knee Society clinical rating system. Clin Orthop Relat Res 248:13–14

    PubMed  Google Scholar 

  17. Kim RH, Scuderi GR, Dennis DA, Nakano SW (2011) Technical challenges of total knee arthroplasty in skeletal dysplasia. Clin Orthop Relat Res 469(1):69–75. doi:10.1007/s11999-010-1516-0

    Article  PubMed Central  PubMed  Google Scholar 

  18. Annual Report (2013) Swedish Hip Arthroplasty Register

  19. Peltonen JI, Hoikka V, Poussa M, Paavilainen T, Kaitila I (1992) Cementless hip arthroplasty in diastrophic dysplasia. J Arthroplasty 7(Suppl):369–376

    Article  PubMed  Google Scholar 

  20. Ritter MA, Davis KE, Davis P, Farris A, Malinzak RA, Berend ME, Meding JB (2013) Preoperative malalignment increases risk of failure after total knee arthroplasty. J Bone Joint Surg Am 95(2):126–131. doi:10.2106/JBJS.K.00607

    Article  PubMed  Google Scholar 

  21. Sorrells RB, Murphy JA, Sheridan KC, Wasielewski RC (2007) The effect of varus and valgus deformity on results of cementless mobile bearing TKA. Knee 14(4):284–288. doi:10.1016/j.knee.2007.04.004

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Orthopaedic Department, HELIOS Endo-Klinik Hamburg, Holstenstr. 2, 22767, Hamburg, Germany

    Daniel Guenther, Daniel Kendoff, Stefan Schmidl, Oliver Jakobs, Thorsten Gehrke & Carl Haasper

  2. Trauma Department, Hannover Medical School (MHH), Carl-Neuberg-Str. 1, 30625, Hannover, Germany

    Daniel Guenther & Mohamed Omar

  3. University of Pittsburgh, Pittsburgh, PA, USA

    Liang Richard Cui

Authors
  1. Daniel Guenther
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  2. Daniel Kendoff
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  3. Mohamed Omar
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  4. Liang Richard Cui
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  5. Stefan Schmidl
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  6. Oliver Jakobs
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  7. Thorsten Gehrke
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  8. Carl Haasper
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Correspondence to Daniel Guenther.

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Guenther, D., Kendoff, D., Omar, M. et al. Total knee arthroplasty in patients with skeletal dysplasia. Arch Orthop Trauma Surg 135, 1163–1167 (2015). https://doi.org/10.1007/s00402-015-2234-6

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  • DOI: https://doi.org/10.1007/s00402-015-2234-6

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