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Treatment of non-union of humerus diaphyseal fractures: a prospective study comparing interlocking nail and locking compression plate

  • Trauma Surgery
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Abstract

Background

The aim of this prospective comparative study was to compare outcomes and complications of humeral diaphyseal fracture non-unions managed with humerus interlocking nail (HIL) and locking compression plate (LCP).

Materials and methods

40 patients with non-union of humeral diaphyseal fractures were included in this study and were randomly allocated in two groups; group A had 20 cases treated with HIL and group B had 20 cases treated with LCP. Clinico-radiological assessments were done for each case up to 2-year follow-up period. Primary outcome measures (time to fracture union, union rate) and secondary outcome measures (functional outcome and complication such as infection, malunion, delayed union, implant failure, joint stiffness and iatrogenic radial nerve palsy) were compared between both the groups. Disabilities of the arm, shoulder and hand (DASH) scoring and Steward and Hundley’s scoring system were used to assess functional outcome of the fracture fixation.

Results

There was no significant difference (p = 0.12) in terms of mean fracture union time between group A (15.8 ± 4.2 weeks) and group B (17.2 ± 3.8 weeks). Group A had 95 % union rate and group B had 100 % union rate (p = 0.14). At the 2-year follow-up visit, there was no significant difference found between both the groups regarding range of motion of shoulder and elbow joint. There was no significant difference found in final functional outcomes between both the groups on comparing DASH score (p = 0.14) and Steward and Hundley’s score (p = 0.08). In terms of complications, there was insignificant difference found between both the groups.

Conclusions

This study concludes that both the implants can be used in non-union of humeral shaft fractures with good functional outcomes and acceptable rate of complications.

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References

  1. Brinker MR, O’Connor DP (2004) The incidence of fractures and dislocations referred for orthopaedic services in a capitated population. J Bone Joint Surg Am 86:290–297

    PubMed  Google Scholar 

  2. Foster RJ, Dixon GL, Bach AW, Appleyard RW, Green TM (1985) Internal fixation of fractures and non-unions of the humeral shaft: indicators and results in a multi-center study. J Bone Joint Surg 67-A:857–864

    Google Scholar 

  3. Wu CC, Shih CH (1992) Treatment for nonunion of the shaft of the humerus: comparison of plates and Seidel interlocking nails. Can J Surg 35(6):661–665

    CAS  PubMed  Google Scholar 

  4. Templeman DC, Sims SA (2007) Humeral shaft fractures. In: Stannard JP, Schmidt AH, Kregor PJ (eds) Surgical treatment of orthopaedic trauma. Thieme Medical Publishers, New York, pp 263–284

    Google Scholar 

  5. Denard A, Richards JE, Obremskey WT, Floyd M, Herzog GA (2010) Outcomes of nonoperative vs operative treatment of humeral shaft fractures: a retrospective study of 213 patients. Orthopedics 33:552

    Google Scholar 

  6. Idoine JD 3rd, French BG, Opalek JM, DeMott L (2012) Plating of acute humeral diaphyseal fractures through an anterior approach in multiple trauma patients. J Orthop Trauma 26:9–18

    Article  PubMed  Google Scholar 

  7. Sarmiento A, Kinman P, Galvin EG, Schmitt RH, Phillips JG (1977) Functional bracing of fractures of the shaft of the humerus. J Bone Joint Surg Am 59:596–601

    CAS  PubMed  Google Scholar 

  8. Zagorski JB, Latta LL, Zych GA, Finnieston AR (1988) Diaphyseal fractures of the humerus. Treatment with prefabricated braces. J Bone Joint Surg Am 70:607–610

    CAS  PubMed  Google Scholar 

  9. Marti RK, Verheyen CC, Besselaar PP (2002) Humeral shaft non-union: evaluation of uniform surgical repair in fifty-one patients. J Orthop Trauma 16(2):108–115

    Article  CAS  PubMed  Google Scholar 

  10. Healy WL, White GM, Mick CA, Brooker AF, Weiland AJ (1987) Nonunion of the humeral shaft. Clin Orthop 219:206–213

    PubMed  Google Scholar 

  11. Foulk DA, Szabo RM (1995) Diaphyseal humerus fractures: natural history and occurrence of nonunion. Orthopedics 18(4):333–335

    CAS  PubMed  Google Scholar 

  12. Cleveland KB (2008) Delayed union and non union of fractures. In: Canale ST, Beaty JH (eds) Campbell’s operative orthopaedics, 11th edn, vol 3. Mosbyp, Philadelphia 3529–3565

  13. Jupiter JB, Wyss H (2010) Stable fixation of osteoporotic fractures and nonunions in the upper limb-life before the “locking plate”. Acta Chir Orthop Traumatol Cech 77:361–364

    CAS  PubMed  Google Scholar 

  14. Lammens J, Bauduin G, Driesen R, Maens P, Stuyck J, De Smet L et al (1998) Treatment of nonunion of the humerus using the Ilizarov external fixator. Clin Orthop 353:223–230

    Article  PubMed  Google Scholar 

  15. Patel VR, Menon DK, Pool RD, Simonis RB (2000) Nonunion of the humerus after failure of surgical treatment management using the Ilizarov circular fixator. J Bone Joint Surg 82-B:977–983

    Article  Google Scholar 

  16. Ring D, Kloen P, Kadzielski J, Helfet D, Jupiter JB (2004) Locking compression plates for osteoporotic nonunions of the diaphyseal humerus. Clin Orthop Relat Res 425:50–54

    Article  PubMed  Google Scholar 

  17. Manish Kiran M, Jee R (2010) Ilizarov’s method for treatment of nonunion of diaphyseal fractures of the humerus. Indian J Orthop 44(4):444–447

    Article  PubMed Central  PubMed  Google Scholar 

  18. Bari MM, Ahmed MU, Hossain MB, Chowdhury FR, Siddiqui MA (2004) Treatment of non union of humerus using GA Ilizarov technique. Mymensingh Med J 13:36–38

    CAS  PubMed  Google Scholar 

  19. Corradi M, Petriccioli D, Panno B, Marenghi P (1996) Seidel locked nailing for the treatment of unstable fractures and nonunion of the humerus. Chir Organi Mov 81(2):189–195

    CAS  PubMed  Google Scholar 

  20. Kumar MN, Ravindranath VP, Ravishankar MR (2013) Outcome of locking compression plates in humeral shaft nonunions. Indian J Orthop 47(2):150–155

    Article  PubMed Central  PubMed  Google Scholar 

  21. Kesemenli CC, Subasi M, Arslan H, Necmioglu S, Kapukaya A (2002) Treatment of humeral diaphyseal nonunions by interlocked nailing and autologous bone grafting. Acta Orthop Belg 68(5):471–475

    CAS  PubMed  Google Scholar 

  22. Hudak PL, Amadio PC, Bombardier C (1996) Development of an upper extremity outcome measure: the DASH (disabilities of the arm, shoulder and hand) [corrected]. The Upper Extremity Collaborative Group (UECG). Am J Ind Med 29:602–608

    Article  CAS  PubMed  Google Scholar 

  23. Stewart MJ, Hundley JM (1955) Fractures of the humerus; a comparative study in methods of treatment. J Bone Joint Surg Am 37-A:681–692

    CAS  PubMed  Google Scholar 

  24. Beguin JM, Plenevaux P, Poilvache G (1991) Considerations concerning the treatment of pseudarthrosis of the humerus. Acta Orthop Belg 57:114–123

    CAS  PubMed  Google Scholar 

  25. Lee M (2005) Nonunions of the humerus. J Hand Ther 18(1):51–53

    Article  Google Scholar 

  26. Chen CM, Chiu FY, Lo WH (2000) Treatment of acute closed humeral shaft fractures with Ender nails. Injury 31(9):683–685

    Article  CAS  PubMed  Google Scholar 

  27. Jupiter JB (1990) Complex non-union of the humeral diaphysis. Treatment with a medial approach, an anterior plate, and a vascularized fibular graft. J Bone Joint Surg Am 72(5):701–707

    CAS  PubMed  Google Scholar 

  28. Bosh U, Skutek M, Kasperczyk WJ, Tscherme H (1999) Nonunion of the humeral diaphysis-operative and nonoperative treatment. Chirurg 70:1202–1208

    Article  Google Scholar 

  29. Wu CC (1996) Humeral shaft nonunion treated by a Seidel interlocking nail with a supplementary staple. Clin Orthop 326:203–208

    Article  PubMed  Google Scholar 

  30. Billings A, Colemon SS (1999) Long-term follow-up of persistent humeral shaft nonunions treated with three-cortical bone grafting and compression plating. Iowa Orthop J 19:31–34

    CAS  PubMed Central  PubMed  Google Scholar 

  31. Nadkarni B, Srivastav S, Mittal V, Agarwal S (2008) Use of locking compression plates for long bone nonunions without removing existing intramedullary nail: review of literature and our experience. J Trauma 65:482–486

    Article  PubMed  Google Scholar 

  32. Pietu G, Raymond G, Letenneur J (1994) Treatment of delayed and nonunions of the humeral shaft using the Seidel locking nail: a preliminary report of five cases. J Orthop Trauma 8(3):240–244

    Article  CAS  PubMed  Google Scholar 

  33. Limbers J, Edmunds I, Ruff S (1998) Huckstep intramedullary nailing for non-union of humeral shaft fractures. Aust NZ J Surg 68:194–198

    Article  CAS  Google Scholar 

  34. Ingman AM, Waters DA (1994) Locked intramedullary nailing of humeral shaft fractures: implant design, surgical technique, and clinical results. J Bone Joint Surg 76(1):23–29

    CAS  Google Scholar 

  35. McKee MD, Miranda MA, Reimer BL, Blasier RB, Redmond BJ, Sims SH et al (1996) Management of humeral nonunions after failure of intramedullary nails. J Orthop Trauma 10:492–499

    Article  CAS  PubMed  Google Scholar 

  36. Kempf I, Grosse A, Karger C (1990) Traitement des pseudarthroses aseptiques du fémur et du tibia par l’enclouage centro-médullaire: apport du verrouillage. In:Cahier d’Enseignement de la SOFCOT, J. Duparc (ed) No 39: Enclouage centro-médullaire, sous le dir. de I Kempf. Expansion Scientifique Française, Paris, p 91–96

  37. Dujardin FH, Mazirt N, Tobenas AC, Duparc F, Thomine JM (2000) Failure of locked nailing for nonunion of the humeral shaft. Rev Chir Orthop 86:773–780

    CAS  PubMed  Google Scholar 

  38. Thomsen NOB, Mikkelsen JB, Svendsen RN, Skovgaard N, Jensen CH, Jorgensen U (1998) Interlocking nailing of humeral shaft fractures. J Orthop Sci 3:199–203

    Article  CAS  PubMed  Google Scholar 

  39. Ajmal M, O’Sullivan M, McCabe J, Curtin W (2001) Antegrade locked intramedullary nailing in humeral shaft fractures. Injury 32:692–694

    Article  CAS  PubMed  Google Scholar 

  40. Bhandari M, Devereaux PJ, McKee MD, Schemitsch EH (2006) Compression plating versus intramedullary nailing of humeral shaft fractures—a meta-analysis. Acta Orthop 77(2):279–284

    Article  PubMed  Google Scholar 

  41. McCormack RG, Brien D, Buckley RE, McKee MD, Powell J, Schemitsch EH (2000) Fixation of fractures of the shaft of the humerus by dynamic compression plate or intramedullary nail: a prospective randomized trial. J Bone Joint Surg Br 82(3):336–339

    Article  CAS  PubMed  Google Scholar 

  42. Rodríguez-Merchán EC (1995) Compression plating versus Hackethal nailing in closed humeral shaft fractures failing nonoperative reduction. J Orthop Trauma 9(3):194–197

    Article  PubMed  Google Scholar 

  43. Brumback RJ, Bosse MJ, Poka A, Burgess AR (1986) Intramedullary stabilization of humeral shaft fractures in patients with multiple trauma. J Bone Joint Surg Am 68(7):960–970

    CAS  PubMed  Google Scholar 

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Correspondence to G. R. Arun.

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Singh, A.K., Arun, G.R., Narsaria, N. et al. Treatment of non-union of humerus diaphyseal fractures: a prospective study comparing interlocking nail and locking compression plate. Arch Orthop Trauma Surg 134, 947–953 (2014). https://doi.org/10.1007/s00402-014-1973-0

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  • DOI: https://doi.org/10.1007/s00402-014-1973-0

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