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Archives of Orthopaedic and Trauma Surgery

, Volume 131, Issue 2, pp 255–259 | Cite as

The clinical efficacy of the vacuum-assisted closure therapy in the management of adult osteomyelitis

  • Y. Tan
  • X. Wang
  • H. Li
  • Q. Zheng
  • J. Li
  • G. Feng
  • Zhijun PanEmail author
Orthopaedic Outcome Assessment

Abstract

Introduction

Vacuum-assisted closure (VAC) therapy is a sophisticated development of a standard surgical procedure. The purpose of this study is to evaluate the clinical efficacy of managing adult osteomyelitis with VAC therapy.

Materials and methods

We included a total of 68 patients that developed osteomyelitis with Cierny–Mader types 2, 3 and 4, and required open wound management between March 2005 and February 2009. In this study, 35 of these patients were treated by VAC therapy and the other 33 by conventional wound management. The patients were well compared with type, debridement times, wounds coverage, bacteriology and recurrence.

Results

Of the study, the patients treated by VAC therapy had a significantly reduced recurrence (1 vs. 7 wounds, P < 0.05), decreased rate of further autodermoplasty or flap surgery (17 vs. 26 wounds, P < 0.05), and increased cases of bacterial species cultures to negative (29 vs. 15 wounds, P < 0.05), debridement times and type were similar between the two groups.

Conclusion

VAC therapy represents a good clinical efficacy in treating osteomyelitis; it can promote the granulation tissue formation, bacterial clearance, and reduce the needs for tissue transfer and muscle flaps in patients. In addition, it could be used as an adjuvant for the eradication of osteomyelitis and improving soft-tissue management, it may be more suitable for treating osteomyelitis with soft-tissue problems.

Keywords

Vacuum-assisted closure Osteomyelitis Debridement Granulation tissue 

Notes

Acknowledgments

This study was supported by the Medicine Health Sciences Fund of Zhejiang (2008A095) and the Natural Science Foundation of Zhejiang (Y208034, Y2100111).

Conflict of interest

The authors had no conflicts of interest to declare in relation to this article.

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Copyright information

© Springer-Verlag 2010

Authors and Affiliations

  • Y. Tan
    • 1
  • X. Wang
    • 1
  • H. Li
    • 1
  • Q. Zheng
    • 1
  • J. Li
    • 1
  • G. Feng
    • 1
  • Zhijun Pan
    • 1
    Email author
  1. 1.Department of Orthopaedic Surgery, The Second Affiliated Hospital, School of MedicineZhejiang UniversityHangzhouChina

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