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Hoffa’s fat pad impingement treated arthroscopically: related findings on preoperative MRI in a case series of 62 patients

  • Arthroscopy and Sports Medicine
  • Published:
Archives of Orthopaedic and Trauma Surgery Aims and scope Submit manuscript

Abstract

Introduction

The morphology of painful impingement of the infrapatellar fat pad (Hoffa’s disease), which is characterized by inflammation, swelling, hypertrophy, fibrosis, and/or calcifications, has been well described. The purpose of this study was to investigate whether corresponding characteristic MRI findings could be assessed in patients with infrapatellar fat pad impingement.

Materials and methods

This study includes 62 patients with secondary symptomatic Hoffa’s fat pad impingement. In these patients, the fat pad was partially resected until no impingement could be determined at full knee movement. Within a maximum of 3 months before arthroscopic surgery, patients had standardized MR imaging using a 1.5 Tesla unit with the following sequences: sagittal T1-TSE, coronal STIR-TSE, transversal fat-suppressed PD-TSE, and sagittal fat-suppressed PD-TSE (Siemens Magnetom Avanto syngo MR B 15). In this case series, the preoperative MRI appearance of the fat pad was evaluated and compared with a cohort of 255 patients without fat pad impingement but with various knee disorders at arthroscopy as well as the same standardized MRI protocol.

Results

In patients with Hoffa’s fat pad impingement, morphologic changes such as localized edema of the superior and/or posterior part of the fat pad, a deep fluid-filled infrapatellar bursa, non-visualization of vertical and/or horizontal clefts, fibrosis, and calcifications were noted on MR imaging with remarkable frequency. Besides a significant enlargement of the fat pad, each of these MRI findings was significantly associated with impingement of Hoffa’s fat pad (P < 0.05). Besides a moderate kappa score for the detection of intrahoffatic calcifications and vertical clefts, kappa values for each finding showed good inter-observer agreement. Results of logistic regression revealed that edema of Hoffa’s fat pad was one of the most important diagnostic MRI criteria for the diagnosis of Hoffa’s fat pad impingement.

Conclusion

MR imaging allows identification of several changes that may be related to a symptomatic impingement of Hoffa’s fat pad. In patients who are suspected of having infrapatellar fat pad impingement, such MRI findings should be considered and distinguished from other causes of anterior knee pain.

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References

  1. Arnoczky SP, Skyhar MJ, Wickiewics TL (1991) Basic science of the knee. In: McGinty JB (ed) Operative Arthroscopy. Raven Press, New York, pp 165–166

    Google Scholar 

  2. Aydingöz U, Oguz B, Aydingöz O, Bayramoglu A, Demiryürek D, Akgün I, Uzün I (2005) Recesses along the posterior margin of the infrapatellar (Hoffa’s) fat pad: prevalence and morphology on routine MR imaging of the knee. Eur Radiol 15(5):988–994

    Article  PubMed  Google Scholar 

  3. Bennell K, Hodges P, Mellor R, Bexander C, Souvlis T (2004) The nature of anterior knee pain following injection of hypertonic saline into the infrapatellar fat pad. J Orthop Res 22(1):116–121

    Article  PubMed  Google Scholar 

  4. Biedert RM, Sanchis-Alfonso V (2002) Sources of anterior knee pain. Clin Sports Med 21(3):335–347

    Article  PubMed  Google Scholar 

  5. Biedert RM, Stauffer E, Friederich NF (1992) Occurrence of free nerve endings in the soft tissue of the knee joint. A histologic investigation. Am J Sports Med 20(4):430–433

    Article  CAS  PubMed  Google Scholar 

  6. Bohnsack M, Wilharm A, Hurschler C, Rühmann O, Stukenborg-Colsman C, Wirth CJ (2004) Biomechanical and kinematic influences of a total infrapatellar fat pad resection on the knee. Am J Sports Med 32(8):1873–1880

    Article  PubMed  Google Scholar 

  7. Borsay J, Dettre G, Nemeth A, Czipott Z, Bachrach D, Kovacs K (1952) Experimental investigations in pathology of Hoffa’s disease. Z Orthop 82(3):420–429

    CAS  PubMed  Google Scholar 

  8. Bowling A (1997) Research Methods in Health. Open University Press, Buckingham

    Google Scholar 

  9. Chung CB, Skaf A, Roger B, Campos J, Stump X, Resnick D (2001) Patellar tendon-lateral femoral condyle friction syndrome: MR imaging in 42 patients. Skeletal Radiol 30(12):694–697

    Article  CAS  PubMed  Google Scholar 

  10. Crossley K, Bennell K, Green S, Cowan S, McConnell J (2002) Physical therapy for patellofemoral pain: a randomized, double-blinded, placebo-controlled trial. Am J Sports Med 30(6):857–865

    PubMed  Google Scholar 

  11. Delcogliano A, Galli M, Menghi A, Belli P (1998) Localized pigmented villonodular synovitis of the knee: report of two cases of fat pad involvement. Arthroscopy 14(5):527–531

    Article  CAS  PubMed  Google Scholar 

  12. Duri ZA, Aichroth PM, Dowd G (1996) The fat pad. Clinical observations. Am J Knee Surg 9(2):55–66

    CAS  PubMed  Google Scholar 

  13. Dye SF, Vaupel GL, Dye CC (1998) Conscious neurosensory mapping of the internal structures of the human knee without intraarticular anesthesia. Am J Sports Med 26(6):773–777

    CAS  PubMed  Google Scholar 

  14. Engelstad BL, Friedman EM, Murphy WA (1981) Diagnosis of joint effusion on lateral and axial projections of the knee. Invest Radiol 16(3):188–192

    Article  CAS  PubMed  Google Scholar 

  15. Hardy P, Muller GP, Got C, Lortat-Jacob A, Benoit J (1998) Glomus tumor of the fat pad. Arthroscopy 14(3):325–328

    Article  CAS  PubMed  Google Scholar 

  16. Hoffa A (1904) The influence of the adipose tissue with regard to the pathology of the knee joint. JAMA 43(12):795–796

    Google Scholar 

  17. Hornuf H, Crasselt C (1975) Hoffa’s fatty tissue hypertrophy as a solitary disease and in combination with meniscus lesion. Beitr Orthop Traumatol 22(12):686–891

    CAS  PubMed  Google Scholar 

  18. Hunziker EB, Stäubli HU, Jakob RP (1990) Surgical anatomy of the knee joint. In: Jakob RB, Stäubli HU (eds) The knee and the cruciate ligaments. Springer, Berlin, pp 31–48

    Google Scholar 

  19. Jacobson JA, Lenchik L, Ruhoy MK, Schweitzer ME, Resnick D (1997) MR imaging of the infrapatellar fat pad of Hoffa. Radiographics 17(3):675–691

    CAS  PubMed  Google Scholar 

  20. Kang CN, Kim DW, Kim DJ, Kim SJ (1999) Intra-articular ganglion cysts of the knee. Arthroscopy 15(4):373–378

    Article  CAS  PubMed  Google Scholar 

  21. Kellermann S (1965) Contribution to chondropathy of the patella. Zentralbl Chir 90(50):2429–2437

    CAS  PubMed  Google Scholar 

  22. Kennedy JC, Alexander IJ, Hayes KC (1982) Nerve supply of the human knee and its functional importance. Am J Sports Med 10(6):329–335

    Article  CAS  PubMed  Google Scholar 

  23. Kohn D, Deiler S, Rudert M (1995) Arterial blood supply of the infrapatellar fat pad. Anatomy and consequences. Arch Orthop Trauma Surg 114(2):72–75

    Article  CAS  PubMed  Google Scholar 

  24. Kosarek FJ, Helms CA (1999) The MR appearance of the infrapatellar plica. Am J Roentgenol 172(2):481–484

    CAS  Google Scholar 

  25. Krenn V, Hofmann S, Engel A (1999) First description of mechanoreceptors in the corpus adiposum infrapatellare of man. Acta Anat 137(2):187–188

    Article  Google Scholar 

  26. Kumar D, Alvand A, Beacon JP (2007) Impingement of infrapatellar fat pad (Hoffa’s disease): results of high-portal arthroscopic resection. Arthroscopy 23(11):1180–1186

    Article  PubMed  Google Scholar 

  27. Landis JR, Koch GG (1977) The measurement of observer agreement for categorical data. Biometrics 33:159–174

    Article  CAS  PubMed  Google Scholar 

  28. La Prade RF (1998) The anatomy of the deep infrapatellar bursa of the knee. Am J Sports Med 26(1):129–132

    Google Scholar 

  29. Lehner B, Koeck FX, Capellino S, Schubert TE, Hofbauer R, Straub RH (2008) Perponderance of sensory versus sympathetic nerve fibers and increased cellularity in the infrapatellar fat pad in anterior knee pain patients after primary arthroplasty. J Orthop Res 26(3):342–350

    Article  PubMed  Google Scholar 

  30. Maculé F, Sastre S, Lasurt S, Sala P, Segur JM, Mallofré C (2005) Hoffa’s fat pad resection in total knee arthroplasty. Acta Orthop Belg 71(6):714–717

    PubMed  Google Scholar 

  31. Magi M, Branca A, Bucca C, Langerame V (1991) Hoffa disease. Ital J Orthop Traumatol 17(2):211–216

    CAS  PubMed  Google Scholar 

  32. McConnell J (2002) The physical therapist’s approach to patellofemoral disorders. Clin Sports Med 21(3):363–387

    Article  PubMed  Google Scholar 

  33. Metheny JA, Mayor MB (1988) Hoffa disease. Chronic impingement of the infrapatellar fat pad. Am J Knee Surg 1:134–139

    Google Scholar 

  34. Murakami S, Muneta T, Ezura Y, Furuya K, Yamamoto H (1997) Quantitative analysis of synovial fibrosis in the infrapatellar fat pad before and after anterior cruciate ligament reconstruction. Am J Sports Med 25(1):29–34

    Article  CAS  PubMed  Google Scholar 

  35. Ogilvie-Harris DJ, Giddens J (1994) Hoffa’s disease: arthroscopic resection of the infrapatellar fat pad. Arthroscopy 10(2):184–187

    Article  CAS  PubMed  Google Scholar 

  36. Özkur A, Adaletli I, Sirikci A, Kervancioglu R, Bayram M (2005) Hoffa’s recess in the infrapatellar fat pad of the knee on MR imaging. Surg Radiol Anat 27(1):61–63

    Article  PubMed  Google Scholar 

  37. Patel SJ, Kaplan PA, Dussault RG, Kahler DM (1998) Anatomy and clinical significance of the horizontal cleft in the infrapatellar fat pad of the knee: MR imaging. Am J Roentgenol 170(6):1551–1555

    CAS  Google Scholar 

  38. Saddik D, McNally EG, Richardson M (2004) MRI of Hoffa’s fat pad. Skeletal Radiol 33(8):433–444

    Article  CAS  PubMed  Google Scholar 

  39. Schweitzer ME, Falk A, Berthoty D, Mitchell M, Resnick D (1992) Knee effusion: normal distribution of fluid. Am J Roentgenol 159(2):361–363

    CAS  Google Scholar 

  40. Shelbourne KD, Patel DV, Martini DJ (1996) Classification and management of arthrofibrosis of the knee after anterior cruciate ligament reconstruction. Am J Sports Med 24(6):857–862

    Article  CAS  PubMed  Google Scholar 

  41. Peng CY, Lee KL, Ingersoll GM (2002) An introduction to logistic regression analysis and reporting. J Educ Res 96(1):3–14

    Article  Google Scholar 

  42. Smillie IS (1962) Injuries of the knee joint. Churchill Livingstone, Edinburgh

    Google Scholar 

  43. Steadman JR, Dragoo JL, Hines SL, Briggs KK (2008) Arthroscopic release for symptomatic scarring of the anterior interval of the knee. Am J Sports Med 36(9):1763–1769

    Article  PubMed  Google Scholar 

  44. Streiner DL, Norman GR (1991) Health measurement scales: a practical guide to their development and use. Oxford University Press, New York

    Google Scholar 

  45. Tschirch FT, Schmid MR, Pfirrmann CW, Romero J, Hodler J, Zanetti M (2003) Prevalence and size of meniscal cysts, ganglionic cysts, synovial cysts of the popliteal space, fluid-filled bursae, and other fluid collections in asymptomatic knees on MR imaging. Am J Roentgenol 180(5):1431–1436

    Google Scholar 

  46. Vahlensieck M, Linneborn G, Schild HH, Schmidt HM (2002) Hoffa’s recess: incidence, morphology and differential diagnosis of the globular-shaped cleft in the infrapatellar fat pad of the knee on MRI and cadaver dissections. Eur Radiol 12(1):90–93

    Article  CAS  PubMed  Google Scholar 

  47. Vahlensieck M, Linneborn G, Schild HH, Schmidt HM (2001) Magnetic resonance imaging (MRI) of the bursa around the knee joint. Rofo 173(3):195–199

    CAS  PubMed  Google Scholar 

  48. Zippel H (1964) Meniscus lesions, meniscus injuries. A study on meniscus operations. Arch Orthop Unfallchir 56:236–247

    Article  CAS  PubMed  Google Scholar 

Download references

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Correspondence to Lars Victor von Engelhardt.

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von Engelhardt, L.V., Tokmakidis, E., Lahner, M. et al. Hoffa’s fat pad impingement treated arthroscopically: related findings on preoperative MRI in a case series of 62 patients. Arch Orthop Trauma Surg 130, 1041–1051 (2010). https://doi.org/10.1007/s00402-010-1133-0

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