Abstract
Esophageal perforation in ankylosing spondylitis (AS) is a rare complication in anterior cervical spine surgery and has not been reported before. A 50-year-old patient with AS developed incomplete tetraplegia after minimal trauma. C5 pedicle fracture was diagnosed and treated predominantly by physical therapy until neurological symptoms progressed. Cervical spine MRI showed C6/7 fracture and spinal cord compression. The patient underwent dorsal laminectomy, C5–7 anterior cervical fusion using allograft iliac crest and CASPAR-plate fixation. Delayed esophageal perforation appeared 10 months postoperatively when he came first to our hospital. He complained of dysphagia and developed acute dyspnea. Posterior stabilization with two plates was performed followed by removal of the ventral plate and screws. The esophageal laceration was sutured. The patient was treated with antibiotics and percutaneous endoscopic gastrostomy. Position of fracture and implants were accurate at 18 months postoperatively. The patient had persistent minor neurological deficits (Frankel D) at last follow-up. We conclude that esophageal perforation after anterior spinal fusion is a rare complication. Minor traumas in patients with AS are unstable and can result in significant spinal injury. Dorsoventral stabilization should be performed to avoid further complications.
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Bavastro P, Schweigert R (1993) Asymptomatische Perforation in den Ösophagus nach Plattenosteosynthese C6/C7. Med Klin 88:670–675
Bernemann D, Harbrecht M (1989) Pharyngeale Komplikationen nach ventralen Fusionsoperationen im Bereiche der Halswirbelsäule. Laryngorhinootologie 68:128–129
Bracken MB, Shepard MJ, Collins WF, Holford TR, Young W, Baskin DS, Eisenberg HM, Flamm E, Leo-Summers L, Maroon J, Marshall LF, Perot PL, Piepmeier J, Sonntag VKH, Wagner FC, Wilberger JE, Winn HR (1990) A randomized, controlled trial of methylprednisolone or naloxone in the treatment of acute spinal-cord injury. Results of the Second National Acute Spinal Cord Injury Study. N Engl J Med 322:1405–1411
Broom MJ, Raycroft JF (1988) Complications of fractures of the cervical spine in ankylosing spondylitis. Spine 13:763–766
Cruickshank B (1971) Pathology of ankylosing spondylitis. Clin Orthop 74:43–58
Do-Koh Y, Lim TH, Won-You J, Eck J, An HS (2001) A biomechanical comparison of modern anterior and posterior plate fixation of the cervical spine. Spine 26:15–21
English GM, Hsu SF, Edgar R, Gibson-Eccles M (1992) Oesophageal trauma in patients with spinal cord injury. Paraplegia 30:903–912
Fox MW, Onofrio BM, Kilgore JE (1993) Neurological complications of ankylosing spondylitis. J Neurosurg 78:871–878
Graham JJ (1989) Complications of cervical spine surgery. A five-year report on a survey of the membership of the Cervical Spine Research Society by the Morbidity and Mortality Committee. Spine 14:1046–1050
Grubb MR, Currier BL, Stone J, Warden KE, An KN (1997) Biomechanical evaluation of posterior cervical stabilization after a wide laminectomy. Spine 22:1948–1954
Halligan M, Hubschmann OR (1993) Short-term and long-term failures of anterior polymethylmethacrylate construct with esophageal perforation. Spine 18:759–761
Hanci M, Toprak M, Sarioglu AC, Kaynar MY, Uzan M, Islak C (1995) Oesophageal perforation subsequent to anterior cervical spine screw/plate fixation. Paraplegia 33:606–609
Hatzitheofilou C, Strahlendorf C, Kakoyiannis S, Charalambides D, Demetriades D (1993) Penetrating external injuries of the oesophagus and pharynx. Br J Surg 80:1147–1149
Hunter T, Dubo H (1978) Spinal fractures complicating ankylosing spondylitis. Ann Intern Med 88:546–549
Hunter T, Dubo HI (1983) Spinal fractures complicating ankylosing spondylitis. A long-term followup study. Arthritis Rheum 26:751–759
Kelly MF, Spiegel J, Rizzo KA, Zwillenberg D (1991) Delayed pharyngoesophageal perforation: a complication of anterior spine surgery. Ann Otol Rhinol Laryngol 100:201–205
Kotani Y, Cunningham BW, Abumi K, McAfee PC (1994) Biomechanical analysis of cervical stabilization systems. An assessment of transpedicular screw fixation in the cervical spine. Spine 19:2529–2539
Kuriloff DB, Blaugrund S, Ryan J, O’Leary P (1987) Delayed neck infection following anterior spine surgery. Laryngoscope 97:1094–1098
Lamesch P, Dralle H, Blauth M, Hauss J, Meyer HJ (1997) Cervicale Oesophagusperforation nach ventraler Fusion der Halswirbelsäule. Chirurg 68:543–547
Lindhorst E, Encke A (1999) Die Ösophagusperforation: Eine seltene Komplikation der Operation degenerativer und traumatischer Halswirbelsäulenleiden. Zentralbl Chir 124:562–567
Murray GC, Persellin RH (1981) Cervical fracture complicating ankylosing spondylitis: a report of eight cases and review of the literature. Am J Med 70:1033–1041
Newhouse KE, Lindsey RW, Clark CR, Lieponis J, Murphy MJ (1989) Esophageal perforation following anterior cervical spine surgery. Spine 14:1051–1053
Pollock RA, Purvis JM, Apple DF, Murray HH (1981) Esophageal and hypopharyngeal injuries in patients with cervical spine trauma. Ann Otol Rhinol Laryngol 90:323–327
Reddin A, Mirvis SE, Diaconis JN (1987) Rupture of the cervical esophagus and trachea associated with cervical spine fracture. J Trauma 27:564–566
Romano PS, Campa DR, Rainwater JA (1997) Elective cervical discectomy in California: postoperative in-hospital complications and their risk factors. Spine 22:2677–2692
Singh K, Vaccaro AR, Kim J, Lorenz EP, Lim TH, An HS (2003) Biomechanical comparison of cervical spine reconstructive techniques after a multilevel corpectomy of the cervical spine. Spine 28:2352–2358
Smith MD, Bolesta MJ (1992) Esophageal perforation after anterior cervical plate fixation: a report of two cases. J Spinal Disord 5:357–362
Thomas JP, Finch R (1991) Esophageal erosion. A complication of acrylic fixation in anterior cervical fusion. Spine 16:1238–1240
Tscherne H, Blauth M (1998) Frakturen bei ankylosierender Spondylitis. In: Tscherne H (ed) Unfallchirurgie Wirbelsäule. Springer, Berlin Heidelberg New York, pp 373–382
Vaccaro R, Conant RF, Hilibrand AS, Albert TJ (2000) A plate-rod device for treatment of cervicothoracic disorders: comparison of mechanical testing with established cervical spine in vitro load testing data. J Spinal Disord 13:350–355
van Berge Henegouwen DP, Roukema JA, de-Nie JC, vd-Werken C 1991) Esophageal perforation during surgery of the cervical spine. Neurosurgery 29:766–768
Weinstein PR, Karpman RR, Gall EP, Pitt M (1982) Spinal cord injury, spinal fracture, and spinal stenosis in ankylosing spondylitis. J Neurosurg 57:609–616
Whitehill R, Sirna EC, Young DC, Cantrell RW (1985) Late oesophageal perforation from an autogenous bone graft. Report of a case. J Bone and Joint Surg Am 67:644–645
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Zdichavsky, M., Blauth, M., Bosch, U. et al. Late esophageal perforation complicating anterior cervical plate fixation in ankylosing spondylitis: a case report and review of the literature. Arch Orthop Trauma Surg 124, 349–353 (2004). https://doi.org/10.1007/s00402-004-0654-9
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DOI: https://doi.org/10.1007/s00402-004-0654-9