Erratum to: Modeling key pathological features of frontotemporal dementia with C9ORF72 repeat expansion in iPSC-derived human neurons

Erratum to: Acta Neuropathol (2013) 126:385–399 DOI 10.1007/s00401-013-1149-y

We regret that the p value was not indicated for Fig. 6c. Below is the revised Fig. 6.

Fig. 6

C9ORF72 repeat expansions form RNA foci in patient iPSCs-derived neurons. Expression levels of C9ORF72 variant 1 (NM_145005.5, isoform b) (a), variant 2 (NM_018325.3, isoform a) (b) and variant 3 (NM_001256054.1, isoform a) (c) in iPSC-derived neurons from two non-carriers and two expanded repeat carriers were assessed by qRT-PCR. Values are mean ± SEM, ***p < 0.001, *p < 0.05 (Student’s t test). FISH analysis was done on control iPSC-derived neurons (d), carrier 1 line 6 iPSC-derived neurons (e), carrier 2 line 11 iPSC-derived neurons (f) using a cy3-conjugated (GGCCCC)₄ probe. Green MAP2. Blue DAPI. Scale bar 10 μm. Quantifications of the percentage of neurons displaying foci (g) and the average number of foci per cell (h) are presented as mean ± SEM, based on analysis of neurons derived from three independent differentiation experiments. Gly-Pro dipeptide repeats are detected by dot blot analysis in neurons of carrier 1 (iPSC lines 5 and 6) and carrier 2 (iPSC lines 1 and 11) (i)