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Dronedarone: Das neue Antiarrhythmikum?

Dronedarone: the new antiarrythmic agent?

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Zusammenfassung

Das Medikament Dronedaron wird als die „Nachfolgesubstanz“ von Amiodaron gehandelt, da ein schnellerer und effektiver Wirkungseintritt bei geringeren Nebenwirkungen zu erwarten ist. Diese Übersichtsarbeit stellt die pharmakologischen Eigenschaften dieses „Multi-Kanal-Blockers“ vor und belegt anhand aktueller Studienergebnisse die erfolgreiche antiarrhythmische Therapie mit Dronedaron bei Patienten mit Vorhofflimmern.

Abstract

Dronedarone is recommended as the successor drug to amiodarone because a faster onset of effects and less side effects are to be expected. This review describes the pharmacological properties of this multi-channel blocker and summarizes the results from recent studies proving successful antiarrhythmic therapy using dronedarone in patients with atrial fibrillation.

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Correspondence to J. Brachmann.

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Brachmann, J., Sinha, AM. Dronedarone: Das neue Antiarrhythmikum?. Herzschr. Elektrophys. 20, 73–75 (2009). https://doi.org/10.1007/s00399-009-0042-9

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