Abstract
The paper discusses the formation, stability, surface and rheological characteristics, as well as in vitro behavior in the gastrointestinal tract of magnetite/cellulose nanocrystals (MCNC)-stabilized olive oil-in-water Pickering emulsions. It has been shown that MCNC-stabilized olive oil-in-water emulsions with a mass percentage of magnetite in the composite of 37–83% are the most resistant to delamination during storage. An increase in the number of acid–base centers is observed for hybrid particles on the oil surface due to their orientation and the formation of a 2D structure. The dynamic viscosity and thixotropic properties of emulsions increase as the zeta potential of drops approaches zero. The stability of emulsions in vitro in oral and gastric phases of gastrointestinal tract and destruction in the medium of the small intestine has been shown. The resulting emulsions can be promising in various biomedical applications due to their high stability, magnetic control, and low toxicity.
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Funding
The reported study was supported by a Grant of the Russian Science Foundation No. 19–73-10091. Investigations were partially carried out using the equipment of the “Khimiya” Common Use Centre (Institute of Chemistry, FRC Komi SC UB RAS).
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VIM: conceptualization, methodology, funding acquisition, project administration, visualization, investigation, and writing—original draft. MAT: conceptualization, methodology, investigation, and writing—original draft. INV: investigation, methodology, and writing—review and editing. ISM: investigation, methodology, and writing—review and editing. PVL: investigation, methodology, and writing—original draft. PAS: supervision, investigation, and writing—original draft.
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Mikhaylov, V.I., Torlopov, M.A., Vaseneva, I.N. et al. Effect of Fe3O4/CNC ratio on properties of olive oil-in-water Pickering emulsions. Colloid Polym Sci 300, 139–152 (2022). https://doi.org/10.1007/s00396-021-04938-y
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DOI: https://doi.org/10.1007/s00396-021-04938-y