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Contact angle hysteresis of bovine serum albumin (BSA) solution/metal (Au-Cr) coated glass substrate

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Abstract

Bovine serum albumin (BSA) has an extraordinary property to carry biomolecules. An experimental study on the wettability of BSA is presented in this study. The variations in the surface tension and the equilibrium contact angle with the change in BSA concentration are also reported. The surface tension and the contact angle are measured with pendant and sessile drop techniques, respectively. A nonlinear decrement in the surface tension with the increment in the BSA concentration is observed. An equilibrium contact angle of a BSA solution with particular concentration is determined by studying the hysteresis in the contact angle from dynamic contact angle measurements. The needle-in-drop technique is used to study the hysteresis of the contact angle. It is observed that the obtained surface tension and the equilibrium contact angle vary with the BSA concentration. In this reported study, for the considered combination of the BSA concentration and solid surface, the liquid drop does not recede as the drop volume decreases, which represents nonreceding contact angle condition. The increment in the contact angle with the increment in the BSA concentration is observed. Finally, it is observed that the inclusion of the proteins not only changes the surface tension but also changes the contact angle.

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Acknowledgement

The authors gratefully acknowledge the funding provided by Alberta Ingenuity, now part of Alberta Innovates-Technology Futures from the Province of Alberta in the form of a scholarship provided to P.R.W.

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Authors and Affiliations

  1. Micro and Nano-scale Transport Laboratory, Department of Mechanical Engineering, University of Alberta, Edmonton, AB, Canada, T6G 2G8

    Prashant R. Waghmare & Sushanta K. Mitra

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  1. Prashant R. Waghmare
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  2. Sushanta K. Mitra
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Correspondence to Sushanta K. Mitra.

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This article is part of the Topical Collection on Contact Angle Hysteresis

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Waghmare, P.R., Mitra, S.K. Contact angle hysteresis of bovine serum albumin (BSA) solution/metal (Au-Cr) coated glass substrate. Colloid Polym Sci 291, 375–381 (2013). https://doi.org/10.1007/s00396-012-2756-1

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  • DOI: https://doi.org/10.1007/s00396-012-2756-1

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