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Molecular imprinting polymerization by Fenton reaction

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Abstract

The aim of this study is the preparation of molecularly imprinted polymers by employing a redox pair as initiator system. Bulk molecularly imprinted polymers were synthesized by using Fenton reagents as initiator system. Theophylline, methacrylic acid, and ethylene glycol dimethacrylate were employed as model template, functional monomer, and crosslinking agent, respectively. Conventional imprinted polymers were also prepared by using 2,2′-azoisobutyronitrile in order to evaluate the efficiency of the proposed initiator system. Redox molecularly imprinted polymers and conventional molecularly imprinted polymers were characterized by water uptake measurement, while the imprinting effect of synthesized polymers were evaluated by performing binding experiments in organic (acetonitrile) and in water (buffered water solution at pH = 7.4) media.

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References

  1. Sibrian-Vazquez M, Spivak DA (2004) Molecular imprinting made easy. J Am Chem Soc 126:7827

    Article  CAS  Google Scholar 

  2. Anderson RA, Ariffin MM, Cormack PAG, Miller EI (2008) Comparison of molecularly imprinted solid-phase extraction (MISPE) with classical solid-phase extraction (SPE) for the detection of benzodiazepines in post-mortem hair samples. Forensic Sci Int 174:40

    Article  CAS  Google Scholar 

  3. Beltran A, Marcé RM, Cormack PAG, Sherrington DC, Borrull F (2009) Selective solid-phase extraction of amoxicillin and cephalexin from urine samples using a molecularly imprinted polymer. J Sep Sci 31:2868

    Article  CAS  Google Scholar 

  4. Puoci F, Iemma F, Cirillo G, Curcio M, Parisi OI, Spizzirri UG, Picci N (2009) New restricted access materials combined to molecularly imprinted polymers for selective recognition/release in water media. Eur Pol J 45:1634

    Article  CAS  Google Scholar 

  5. Beltran A, Marcé RM, Cormack PAG, Borrull F (2009) Synthesis by precipitation polymerisation of molecularly imprinted polymer microspheres for the selective extraction of carbamazepine and oxcarbazepine from human urine. J Chromatogr A 1216:2248

    Article  CAS  Google Scholar 

  6. Santos WDJR, Lima PR, Tarley CRT, Höehr NF, Kubota LT (2009) Synthesis and application of a peroxidase-like molecularly imprinted polymer based on hemin for selective determination of serotonin in blood serum. Anal Chim Acta 631:170

    Article  CAS  Google Scholar 

  7. Puoci F, Iemma F, Picci N (2008) Stimuli-responsive molecularly imprinted polymers for drug delivery: a review. Current Drug Deliv 5:85

    Article  CAS  Google Scholar 

  8. Simms RW, Cunningham MF (2007) High molecular weight poly(butyl methacrylate) by reverse atom transfer radical polymerization in miniemulsion initiated by a redox system. Macromolecules 40:860

    Article  CAS  Google Scholar 

  9. Theodoridis G, Zacharis CK, Tzanavaras PD, Themelis DG, Economou A (2004) J Chromatogr A 1030:69

    Article  CAS  Google Scholar 

  10. Farrington K, Magner E, Regan F (2006) Predicting the performance of molecularly imprinted polymers: selective extraction of caffeine by molecularly imprinted solid phase extraction. Anal Chim Acta 566:60

    Article  CAS  Google Scholar 

  11. Barros JAG, Fechine GKM, Alcantara MR, Catalani LH (2006) Poly(N-vinyl-2-pyrrolidone) hydrogels produced by Fenton reaction. Polymer 47:8414

    Article  CAS  Google Scholar 

  12. Boonpangrak S, Whitcombe MJ, Prachayasittikul V, Mosbach K, Ye L (2006) Preparation of molecularly imprinted polymers using nitroxide-mediated living radical polymerization. Biosens Bioelect 22:349

    Article  CAS  Google Scholar 

  13. Cheong SH, McNiven S, Rachkov A, Levi R, Yano K, Karube I (1997) Testosterone receptor binding mimic constructed using molecular imprinting. Macromolecules 30:1317–1322

    Article  CAS  Google Scholar 

  14. Puoci F, Cirillo G, Curcio M, Iemma F, Parisi OI, Castiglione M, Picci N (2008) Molecularly imprinted polymers for α-tocopherol delivery. Drug Deliv 15:253

    Article  CAS  Google Scholar 

  15. Urraca JL, Moreno-Bondi MC, Hall AJ, Sellergen B (2007) Direct extraction of penicillin G and derivatives from aqueous samples using a stoichiometrically imprinted polymer. Anal Chem 79:695

    Article  CAS  Google Scholar 

  16. Curcio M, Puoci F, Iemma F, Parisi OI, Cirillo G, Spizzirri UG, Picci N (2009) Covalent insertion of antioxidant molecules on chitosan by a free radical grafting procedure. J Agric Food Chem 57:5933

    Article  CAS  Google Scholar 

  17. Pignatello JJ (1992) Dark and photoassisted Fe3+-catalyzed degradation of chlorophenoxy herbicides by hydrogen peroxide. Environ Sci Technol 26:944

    Article  CAS  Google Scholar 

  18. Wang X, Brusseau ML (1998) Effect of pyrophosphate on the dechlorination of tetrachloroethene by the Fenton reaction. Environ Toxicol Chem 17:1689

    Article  CAS  Google Scholar 

  19. Sun Y-M, Huang T-L (1995) Pervaporation of ethanol–water mixtures through poly(vinyl alcohol-g-acrylic acid) membranes prepared by use of Fenton's reagent in grafting. J Polym Res 2:47

    Article  CAS  Google Scholar 

  20. Ye L, Mosbach K (2008) Molecular imprinting: synthetic materials as substitutes for biological antibodies and receptors. Chem Mater 20:859

    Article  CAS  Google Scholar 

  21. Gore MA, Karmalkar RN, Kulkarni MG (2004) Enhanced capacities and selectivities for cholesterol in aqueous media by molecular imprinting: role of novel cross-linkers. J Chromatogr B 804:211

    Article  CAS  Google Scholar 

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Acknowledgment

This work was financially supported by University funds.

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Authors and Affiliations

  1. Dipartimento di Scienze Farmaceutiche, Università della Calabria, Edificio Polifunzionale, Arcavacata di Rende, CS, 87036, Italy

    Giuseppe Cirillo, Francesco Puoci, Manuela Curcio, Ortensia Ilaria Parisi, Francesca Iemma, Umile Gianfranco Spizzirri & Nevio Picci

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  1. Giuseppe Cirillo
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  2. Francesco Puoci
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  3. Manuela Curcio
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  4. Ortensia Ilaria Parisi
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  5. Francesca Iemma
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  6. Umile Gianfranco Spizzirri
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  7. Nevio Picci
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Correspondence to Francesco Puoci.

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Cirillo, G., Puoci, F., Curcio, M. et al. Molecular imprinting polymerization by Fenton reaction. Colloid Polym Sci 288, 689–693 (2010). https://doi.org/10.1007/s00396-010-2198-6

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  • DOI: https://doi.org/10.1007/s00396-010-2198-6

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