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Determination of intrinsic viscosities of macromolecules and nanoparticles. Comparison of single-point and dilution procedures

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Abstract

The determination of the intrinsic viscosity by single-point determinations, like that based on the Solomon–Ciuta equation, have been proposed as efficient alternatives to dilution procedures. With a basis on theoretical analysis and computer simulation, we evaluate the systematic and global bias of the Solomon–Ciuta result and show how it depends on the strength of the concentration dependence of the solution viscosity (represented by the intrinsic viscosity and the Huggins constant) and the concentration of the single measured solution. We propose that an estimated Huggins constant can be employed in a corrected Solomon–Ciuta procedure, which may yield results for the intrinsic viscosity that are even more accurate than those from the Huggins extrapolation. This gives support and utility to the use of the single-point procedure when the intrinsic viscosity has to be determined for a unique concentration. We also pinpoint specific circumstances where the dilution–extrapolation procedures should be preferred.

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Acknowledgements

This work was performed within a Grupo de Excelencia de la Región de Murcia (grant 04531/GERM/06). Support was also provided by grant CTQ-2006-06831 from Ministerio de Educación y Ciencia (MEC), including FEDER funds. J.G.H.C. was the recipient of a Ramón y Cajal postdoctoral contract and R.P. acknowledges a predoctoral fellowship from MEC.

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Authors and Affiliations

  1. Departamento de Química Física, Facultad de Química, Universidad de Murcia, 30071, Murcia, Spain

    Ramón Pamies, José Ginés Hernández Cifre, María del Carmen López Martínez & José García de la Torre

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  1. Ramón Pamies
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  2. José Ginés Hernández Cifre
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  3. María del Carmen López Martínez
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  4. José García de la Torre
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Correspondence to José García de la Torre.

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Pamies, R., Hernández Cifre, J.G., del Carmen López Martínez, M. et al. Determination of intrinsic viscosities of macromolecules and nanoparticles. Comparison of single-point and dilution procedures. Colloid Polym Sci 286, 1223–1231 (2008). https://doi.org/10.1007/s00396-008-1902-2

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  • DOI: https://doi.org/10.1007/s00396-008-1902-2

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