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Investigation of PEG 6000/Tween 80/Span 80/H2O niosome microstructure

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Abstract

A stable niosome is prepared from Poly(ethylene glycol) [PEG] 6000/Tween 80/Span 80/H2O lamellar liquid crystal. The niosome structures and properties are studied by the methods of negative-staining transmission electron microscopy and small angle X-ray diffraction. A new calculating method is first put forward to obtain the microstructure and layer number of the niosome membrane. The membrane thickness and layer number of the niosome are 8–22 nm and 1–3.5 in PEG 6000/Tween 80/Span 80/H2O system.

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Acknowledgment

This work was supported by the National Natural Science Foundation of China (20573091, 20233010).

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Authors and Affiliations

  1. School of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou, Jinagsu, 25002, People’s Republic of China

    Tianqing Liu & Rong Guo

  2. School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, Jinagsu, 210093, People’s Republic of China

    Tianqing Liu & Rong Guo

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  1. Tianqing Liu
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  2. Rong Guo
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Correspondence to Rong Guo.

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Liu, T., Guo, R. Investigation of PEG 6000/Tween 80/Span 80/H2O niosome microstructure. Colloid Polym Sci 285, 711–713 (2007). https://doi.org/10.1007/s00396-006-1627-z

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  • DOI: https://doi.org/10.1007/s00396-006-1627-z

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