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Aggregation behavior of amphiphilic poly(2-alkyl-2-oxazoline) diblock copolymers in aqueous solution studied by fluorescence correlation spectroscopy

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An Erratum to this article was published on 15 September 2004

Abstract

The diffusional behavior of amphiphilic poly(2-oxazoline) diblock copolymers in aqueous solution is studied using photon correlation spectroscopy (PCS) and fluorescence correlation spectroscopy (FCS). The polymers were synthesized by living cationic polymerization and were fluorescence-labeled with tetramethyl rhodamine isothiocyanate either at the end of the hydrophilic or the hydrophobic block. Temperature-resolved PCS showed that, at room temperature, large metastable aggregates are present along with unimers and micelles. An annealing above ~40 °C resulted in stable equilibrium micellar solutions. By means of FCS, the hydrodynamic radii of the unimers and the micelles were measured simultaneously in a broad concentration range, and the critical micelle concentration could be determined. Comparison of the results from conventional PCS measurements with this first FCS study showed excellent agreement and the high potential of the FCS technique.

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Scheme 1.a
Fig. 1a,b
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Acknowledgements

We wish to thank F. Kremer, Fakultät für Physik und Geowissenschaften, Universität Leipzig, for financial support and fruitful discussions and U. Hahn, A. Beck-Sickinger, and T. Greiner-Stöffele, Fakultät für Biowissenschaften, Pharmazie und Psychologie, Universität Leipzig, for providing the FCS instrument and for help with the measurements. We also gratefully acknowledge financial support by the Deutsche Forschungsgemeinschaft, by the European Union under a Marie Curie Training Site program (contract No. HPMT-CT-2001-00396) and by the Grant Agency of the Academy of Sciences of the Czech Republic (grant No. 4050403).

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  1. Tune B. Bonné & Christine M. Papadakis

    Present address: Physik Department E13, Technische Universität München, James-Franck-Str. 1, 85747, Garching, Germany

Authors and Affiliations

  1. Fakultät für Physik und Geowissenschaften, Universität Leipzig, Linnéstr. 5, 04103, Leipzig, Germany

    Tune B. Bonné & Christine M. Papadakis

  2. Chemie Department, Technische Universität München, Lichtenbergstr. 4, 85747, Garching, Germany

    Karin Lüdtke & Rainer Jordan

  3. Institute of Macromolecular Chemistry, Academy of Sciences of the Czech Republic, Heyrovsky Sq. 2, CZ-16206, Prague, Czech Republic

    Petr Štěpánek

  4. Department of Chemistry, Chemical Engineering and Materials Science, Polytechnic University, Six Metrotech Center, Brooklyn, NY , 11201, USA

    Rainer Jordan

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  1. Tune B. Bonné
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Correspondence to Christine M. Papadakis.

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Dedicated to Prof. Dr. Erhard W. Fischer on the occasion of his 75th birthday

An erratum to this article can be found at http://dx.doi.org/10.1007/s00396-004-1196-y

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Bonné, T.B., Lüdtke, K., Jordan, R. et al. Aggregation behavior of amphiphilic poly(2-alkyl-2-oxazoline) diblock copolymers in aqueous solution studied by fluorescence correlation spectroscopy. Colloid Polym Sci 282, 833–843 (2004). https://doi.org/10.1007/s00396-004-1131-2

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