Effects of high intake of cod or salmon on gut microbiota profile, faecal output and serum concentrations of lipids and bile acids in overweight adults: a randomised clinical trial

Table 7 Spearman’s correlations of serum and urine concentrations of trimethylamine N-oxide (TMAO) and 1-methylhistidine (1-MeHis) with gut microbiota combined for Cod group, Salmon group and Control group, showing only correlations where at least one bacterial probe is significantly correlated with TMAO or 1-MeHis

Counts	Serum (µmol/l)		Urine (µmol/mmol creatinine)
Counts	TMAO	1-MeHis	TMAO	1-MeHis
Baseline
Akkermansia muciniphila	0.416^*	0.366^*	0.375^*	0.084
Bacteroides sp.	0.200	− 0.068	0.372^*	− 0.066
Clostridium methylpentosum	− 0.350^*	0.096	− 0.073	0.218
Coprobacillus_cateniformis	0.229	− 0.085	0.047	− 0.011
Eubacterium rectale	− 0.115	0.086	− 0.071	0.141
Lachnosp Incertae Sedis	− 0.186	0.382^*	− 0.127	0.331
Mycoplasma hominis	0.253	0.100	0.298	0.232
Phascolarctobacterium faecium	0.129	0.437^*	0.212	0.222
Proteobacteria	0.201	0.166	0.358^*	0.064
Staphylococcus epidermidis	− 0.213	0.125	− 0.294	0.136
Streptococcus agalactiae	− 0.297	− 0.117	− 0.148	0.085
Endpoint
Akkermansia muciniphila	0.306	− 0.022	− 0.142	− 0.106
Bacteroides sp.	− 0.128	0.103	− 0.417^*	− 0.087
Clostridium methylpentosum	0.135	− 0.077	0.106	− 0.097
Coprobacillus cateniformis	− 0.025	− 0.079	− 0.163	− 0.415^*
Eubacterium rectale	− 0.130	− 0.384^*	− 0.286	− 0.482^**
Lachnosp Incertae Sedis	− 0.059	− 0.214	− 0.265	− 0.338
Mycoplasma hominis	0.080	0.151	− 0.040	0.371^*
Phascolarctobacterium faecium	0.201	0.272	− 0.223	− 0.216
Proteobacteria	0.089	− 0.062	0.126	0.034
Staphylococcus epidermidis	− 0.121	− 0.321	− 0.307	− 0.364^*
Streptococcus agalactiae	− 0.233	− 0.310	− 0.282	− 0.513^**