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Activation of T-regulatory cells by a synbiotic may be important for its anti-inflammatory effect

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References

  1. Moser AM, Spindelboeck W, Halwachs B, Strohmaier H, Kump P, Gorkiewicz G, Hogenauer C (2018) Effects of an oral synbiotic on the gastrointestinal immune system and microbiota in patients with diarrhea-predominant irritable bowel syndrome. Eur J Nutr. https://doi.org/10.1007/s00394-018-1826-7

    Article  PubMed  PubMed Central  Google Scholar 

  2. Chen J, Vitetta L (2018) Inflammation-modulating effect of butyrate in the prevention of colon cancer by dietary fiber. Clin Colorectal Cancer 17(3):e541–e544

    Article  Google Scholar 

  3. Ford AC, Lacy BE, Talley NJ (2017) Irritable bowel syndrome. N Engl J Med 376(26):2566–2578

    Article  CAS  Google Scholar 

  4. Tap J, Derrien M, Tornblom H, Brazeilles R, Cools-Portier S, Dore J, Storsrud S, Le Neve B, Ohman L, Simren M (2017) Identification of an intestinal microbiota signature associated with severity of irritable bowel syndrome. Gastroenterology 152(1):111–123e118

    Article  Google Scholar 

  5. Shariati A, Fallah F, Pormohammad A, Taghipour A, Safari H, Chirani AS, Sabour S, Alizadeh-Sani M, Azimi T (2019) The possible role of bacteria, viruses, and parasites in initiation and exacerbation of irritable bowel syndrome. J Cell Physiol 234(6):8550–8569

    Article  CAS  Google Scholar 

  6. Lee MK, Xu S, Fitzpatrick EH, Sharma A, Graves HL, Czerniecki BJ (2013) Inhibition of CD4+ CD25+ regulatory T cell function and conversion into Th1-like effectors by a Toll-like receptor-activated dendritic cell vaccine. PLoS One 8(11):e74698

    Article  CAS  Google Scholar 

  7. Pimentel M, Lembo A, Chey WD, Zakko S, Ringel Y, Yu J, Mareya SM, Shaw AL, Bortey E, Forbes WP (2011) Rifaximin therapy for patients with irritable bowel syndrome without constipation. N Engl J Med 364(1):22–32

    Article  CAS  Google Scholar 

  8. Lembo A, Pimentel M, Rao SS, Schoenfeld P, Cash B, Weinstock LB, Paterson C, Bortey E, Forbes WP (2016) Repeat treatment with rifaximin is safe and effective in patients with diarrhea-predominant irritable bowel syndrome. Gastroenterology 151(6):1113–1121

    Article  CAS  Google Scholar 

  9. Fuke N, Aizawa K, Suganuma H, Takagi T, Naito Y (2017) Effect of combined consumption of Lactobacillus brevis KB290 and beta-carotene on minor diarrhoea-predominant irritable bowel syndrome-like symptoms in healthy subjects: a randomised, double-blind, placebo-controlled, parallel-group trial. Int J Food Sci Nutr 68(8):973–986

    Article  CAS  Google Scholar 

  10. Alrafas HR, Busbee PB, Nagarkatti M, Nagarkatti PS (2019) Resveratrol modulates the gut microbiota to prevent murine colitis development through induction of Tregs and suppression of Th17 cells. J Leukoc Biol 106(2):467–480. https://doi.org/10.1002/JLB.3A1218-476RR

    Article  CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. Medlab Clinical Ltd, Sydney, 2015, Australia

    Jiezhong Chen & Luis Vitetta

  2. Faculty of Medicine and Health, The University of Sydney, Sydney, 2006, Australia

    Luis Vitetta

Authors
  1. Jiezhong Chen
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  2. Luis Vitetta
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Correspondence to Luis Vitetta.

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Chen, J., Vitetta, L. Activation of T-regulatory cells by a synbiotic may be important for its anti-inflammatory effect. Eur J Nutr 58, 3379–3380 (2019). https://doi.org/10.1007/s00394-019-02080-8

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  • DOI: https://doi.org/10.1007/s00394-019-02080-8

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