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European Journal of Nutrition

, Volume 57, Issue 8, pp 2839–2846 | Cite as

Association between dietary zinc intake and mortality among Chinese adults: findings from 10-year follow-up in the Jiangsu Nutrition Study

  • Zumin ShiEmail author
  • Anna Chu
  • Shiqi Zhen
  • Anne W. Taylor
  • Yue Dai
  • Malcolm Riley
  • Samir Samman
Original Contribution

Abstract

Purpose

Population studies of the association between zinc intake and mortality yield inconsistent findings. Using data from Jiangsu Nutrition Study, we aimed to assess the association between zinc intake and mortality among Chinese adults.

Methods

We prospectively studied 2832 adults aged 20 years and older with a mean follow-up of 9.8 years. At baseline, food intake was measured by 3-day weighed food record (WFR) between September and December in 2002. Death occurrence was assessed in 2012 during a household visit as well as by data linkage with the regional death registry. Hazard ratios (HRs) and 95% CI were calculated using competing risks regression (CVD and cancer mortality) and Cox proportional hazards analysis (all-cause mortality).

Results

During 27,742 person-years of follow-up, there were 184 deaths [63 cancer deaths and 70 cardiovascular disease (CVD) deaths]. Dietary zinc to energy ratio was positively associated with cancer and all-cause mortality. Across quartiles of the zinc to energy ratio from low to high, the HR (95% CI) for all-cause mortality was 1.00, 1.80 (95% CI 1.10–2.95), 1.55 (95% CI 0.96–2.50), and 1.85 (95% CI 1.11–3.07), respectively. Comparing the extreme quartiles of the zinc to energy ratio, the HR for cancer mortality was 2.28 (95% CI 1.03–5.04).

Conclusion

Zinc intake was positively related to all-cause mortality and cancer mortality.

Keywords

Zinc intake Mortality Chinese Cohort study 

Notes

Acknowledgements

The authors thank the participating regional Centres for Disease Control and Prevention in Jiangsu province, including the Nanjing, Xuzhou, Jiangyin, Taicang, Suining, Jurong, Sihong, and Haimen Centres for their support in data collection.

Compliance with ethical standards

Conflict of interest

The authors have no relevant financial interest in the subject matter of this article.

Supplementary material

394_2017_1551_MOESM1_ESM.docx (49 kb)
Supplementary material 1 (DOCX 49 KB)

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Copyright information

© Springer-Verlag GmbH Germany 2017

Authors and Affiliations

  1. 1.Department of Nutrition and Foodborne Disease PreventionJiangsu Provincial Center for Disease Control and PreventionNanjingChina
  2. 2.Discipline of Medicine, Adelaide Medical SchoolUniversity of AdelaideAdelaideAustralia
  3. 3.Department of Human NutritionThe University of OtagoDunedinNew Zealand
  4. 4.Commonwealth Scientific and Industrial Research Organisation (CSIRO)AdelaideAustralia
  5. 5.School of Life and Environmental SciencesUniversity of SydneySydneyAustralia

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