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Coffee consumption, obesity and type 2 diabetes: a mini-review

European Journal of Nutrition volume 55, pages 1345–1358 (2016)Cite this article

Abstract

Purpose

The effects of regular coffee intake on weight gain and development of diabetes are reviewed. The pathophysiology of obesity and type 2 diabetes as well as the necessity of preventive options based on the increasing prevalence of these two disorders worldwide is briefly discussed. The relationship between weight gain and development of diabetes is also presented. The two major constituents in the brewed coffee, chlorogenic acids and caffeine, are responsible for many of the beneficial effects suggested by numerous epidemiological studies of coffee consumption and the development of diabetes.

Methods

A wide search of various databases, such as PubMed and Google Scholar, preceded the writing of this manuscript, focusing on key words that are part of the title. It was selected mainly review papers from in vivo, ex vivo, in vitro experimental studies in animals and human tissues as well as wide population-based epidemiological studies in the last 10 years.

Conclusion

As of today, there are mounting evidences of the reduced risk of developing type 2 diabetes by regular coffee drinkers of 3–4 cups a day. The effects are likely due to the presence of chlorogenic acids and caffeine, the two constituents of coffee in higher concentration after the roasting process.

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Acknowledgments

The authors would like to acknowledge the fundamental support from Mrs. Valerie Yaughn, Director of the Library at South University, Savannah Campus, in helping to find peer-reviewed papers that were of interest and Julius Hornstein, who offered to revise my manuscript. Dr. Darcy Lima passed away last July 2015, and I wanted to acknowledge his infinite encouragement to write this and many other papers, book chapters and books we wrote together. He will be forever remembered and his memory a continuous source of support and a model to be followed.

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Authors and Affiliations

  1. Department of Pharmaceutical Sciences, South University School of Pharmacy, 709 Mall Boulevard, Savannah, GA, 31419, USA

    Roseane Maria Maia Santos

  2. Instituto de Neurologia Deolindo Couto, Universidade Federal do Rio de Janeiro, Botafogo, Rio de Janeiro, Brazil

    Darcy Roberto Andrade Lima

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  1. Roseane Maria Maia Santos
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  2. Darcy Roberto Andrade Lima
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Correspondence to Roseane Maria Maia Santos.

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D. R. A. Lima: Deceased.

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Santos, R.M.M., Lima, D.R.A. Coffee consumption, obesity and type 2 diabetes: a mini-review. Eur J Nutr 55, 1345–1358 (2016). https://doi.org/10.1007/s00394-016-1206-0

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Keywords

  • Coffee
  • Obesity
  • Diabetes
  • Chlorogenic acid
  • Caffeine