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Long-term dietary intake of selenium, calcium, and dairy products is associated with improved capillary recruitment in healthy young men

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Abstract

Purpose

To identify associations between long-term (1 year) food intake and skin nutritive microvascular function in healthy subjects.

Methods

This was a cross-sectional study. A validated 88-item food-frequency questionnaire was administered to 39 healthy men aged 23.4 ± 0.5 years and body mass index 23.3 ± 2.3 kg/m2, who reported food intake during the last year and underwent videocapillaroscopy exams. The main outcome was the increase in functional capillary recruitment, that is, peak capillary density after post-occlusive reactive hyperemia subtracted from basal capillary density (caps/mm2). Associations between reported food intake and functional capillary recruitment were investigated.

Results

Daily average estimates of intake were: total energy (3,745 ± 1,365 kcal), carbohydrates (60.1 ± 5.9 %), lipids (22.1 ± 4.4 %), proteins (17.8 ± 4.1 %), fibers (33.9 ± 18.5 g), and cholesterol (492.8 ± 209.6 mg). Positive significant correlations with capillary recruitment were found for selenium (as μg/day/1,000 kcal; rho = 0.3412, p = 0.038,) calcium (as mg/day/1,000 kcal; rho = 0.3390, p = 0.043), and percentage of total energy from dairy products (rho = 0.3660, p = 0.023).

Conclusions

Long-term intakes of selenium, calcium, and dairy products were positively associated with capillary recruitment in skin nutritive microcirculation in healthy young men. The role of such dietary components is discussed and possible mechanisms for their effects should be further investigated. This evidence adds one more possible functional property of these nutrients and food items.

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Acknowledgments

National Council for Scientific and Technological Development (CNPq, 141690/2008-9); State of Rio de Janeiro Carlos Chagas Filho Research Foundation (FAPERJ); Financing Agency of Studies and Projects (FINEP) and Coordination for the Enhancement of Education Personnel (CAPES).

Conflict of interest

The authors declare that they have no conflict of interest.

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Authors and Affiliations

  1. Clinical and Experimental Research Laboratory on Vascular Biology, BioVasc, Biomedical Center, State University of Rio de Janeiro, Rua São Francisco Xavier, 524, Maracanã, UERJ, Pavilhão Haroldo Lisboa da Cunha, Sala 104 (BioVasc), Térreo, Rio de Janeiro, CEP: 20550-013, Brazil

    Caroline Buss, Carolina Marinho, Priscila Alves Maranhão & Eliete Bouskela

  2. Endocrinology, Department of Internal Medicine, Medical Sciences Faculty, State University of Rio de Janeiro, Av. 28 de Setembro, 77. Vila Isabel, Rio de Janeiro, Brazil

    Luiz Guilherme Kraemer-Aguiar

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  1. Caroline Buss
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  2. Carolina Marinho
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  3. Priscila Alves Maranhão
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  4. Eliete Bouskela
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  5. Luiz Guilherme Kraemer-Aguiar
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Correspondence to Caroline Buss.

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Buss, C., Marinho, C., Maranhão, P.A. et al. Long-term dietary intake of selenium, calcium, and dairy products is associated with improved capillary recruitment in healthy young men. Eur J Nutr 52, 1099–1105 (2013). https://doi.org/10.1007/s00394-012-0419-0

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  • DOI: https://doi.org/10.1007/s00394-012-0419-0

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