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Adulter Morbus Still, Fieber, Diagnose und Therapie

Adult onset Still’s disease, fever, diagnosis and therapy

Zeitschrift für Rheumatologie volume 71, pages 174–180 (2012)Cite this article

Zusammenfassung

Der adulte Morbus Still (engl. „adult onset Still’s disease“, AOSD) mit einer Inzidenz zwischen 1 und 3 Fällen pro 1 Mio. Einwohner gehört zu den diagnostisch aufwendigsten Fiebererkrankungen. Das Fehlen von Biomarkern und seine Ähnlichkeit mit infektiösen, malignen und rheumatischen Erkrankungen führt häufig zu einer protrahierten Diagnose. Der vorliegende Beitrag soll daher versuchen, über den Kenntnisstand der klinisch relevanten Symptome, die Laborparameter für die Diagnostik des AOSD sowie die neuen Therapiemöglichkeiten eine Übersicht zu geben.

Abstract

Adult onset Still’s disease (AOSD) with an incidence of 1–3 cases per 1 million belongs to the most difficult diagnosis of febrile diseases. The lack of biomarkers and its similarity to infectious and malignant and rheumatic diseases lead to a prolongation of its diagnosis. The following report focuses on providing an overview of the current knowledge of relevant symptoms and laboratory parameters for the diagnosis of AOSD and new treatment possibilities.

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  1. Klinik für Immunologie und Rheumatologie, Medizinische Hochschule Hannover, Carl-Neuberg Str. 1, 30625, Hannover, Deutschland

    N.T. Baerlecken & R.E. Schmidt

Authors
  1. N.T. Baerlecken
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  2. R.E. Schmidt
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Correspondence to N.T. Baerlecken.

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Baerlecken, N., Schmidt, R. Adulter Morbus Still, Fieber, Diagnose und Therapie. Z. Rheumatol. 71, 174–180 (2012). https://doi.org/10.1007/s00393-011-0859-6

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  • DOI: https://doi.org/10.1007/s00393-011-0859-6

Schlüsselwörter

  • Morbus Still
  • Adulter Morbus Still
  • Fieber
  • Still-Exanthem
  • Fiebersyndrome

Keywords

  • Still’s disease
  • Adult onset Still’s disease
  • Fever
  • Still’s exanthema
  • Febrile syndrome