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Enteropathische Arthritis

Wasser im Darm, Feuer im Gelenk

Enteropathic arthritis

Water in the intestines, fire in the joints

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Zusammenfassung

Bei einer Reihe intestinaler Erkrankungen kann es neben der abdominellen Symptomatik zur Beteiligung von Gelenken kommen, die die Lebensqualität der Patienten zusätzlich einschränkt.

Als enteropathische Arthritiden (EA) werden diejenigen Gelenkentzündungen bezeichnet, die im Rahmen chronisch entzündlicher Darmerkrankungen, bei M. Whipple oder nach einem chirurgisch hergestellten intestinalen Bypass auftreten. Den Grunderkrankungen gemeinsam ist eine gestörte Schrankenfunktion der Darmwand mit konsekutiver immunologischer Dysregulation und Gelenkentzündung.

Abstract

Patients with various kinds of intestinal illnesses sometimes suffer not only abdominal symptoms, but also joint involvement, leading to a reduction in quality of life.

Diseases leading to inflammatory joint involvement such as inflammatory bowel disease, Whipple’s disease or surgical intestinal bypass, are classified as enteropathic arthritis. In all cases, disrupted barrier function of the intestine causes activation of the immune system and inflammation of joints.

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Interessenkonflikt

Die korrespondierende Autorin weist auf folgende Beziehungen hin: Vortragstätigkeit für die Firmen Essex Pharma, Abbott, Wyeth und Roche.

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  1. Medizinische Klinik 3, Rheumatologie und Immunologie, Universität Erlangen-Nürnberg, Ulmenweg 18, 91054, Erlangen, Deutschland

    M. Ronneberger

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  1. M. Ronneberger
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Correspondence to M. Ronneberger.

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Ronneberger, M. Enteropathische Arthritis. Z. Rheumatol. 68, 329–336 (2009). https://doi.org/10.1007/s00393-009-0465-z

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  • DOI: https://doi.org/10.1007/s00393-009-0465-z

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