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Selbstlimitation entzündlicher T-Zell-Antworten

Hilfe zur Selbsthilfe als therapeutisches Konzept

Self-limitation of inflammatory T-cell responses

Help to self-help as a therapeutic concept

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Zusammenfassung

Regulatorische T-Zellen bilden einen Forschungsschwerpunkt auf dem Gebiet der Autoimmunität. Neuere Ergebnisse zeigen jedoch, dass proinflammatorische TH1-Zellen selbst wichtige immunregulatorische Funktionen ausüben. Dieser physiologische Selbstkontrollmechanismus besitzt großes therapeutisches Potenzial.

Abstract

Regulatory T cells are in the focus of research on autoimmunity. However, recent findings suggest that pro-inflammatory TH1 cells themselves exert important immunoregulatory functions. This physiological self-limiting mechanism holds great promise for therapeutic interventions.

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Authors and Affiliations

  1. Deutsches Rheuma-Forschungszentrum, Charitéplatz 1, 10117, Berlin, Deutschland

    S. Rutz & A. Scheffold

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  1. S. Rutz
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  2. A. Scheffold
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Correspondence to A. Scheffold.

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Rutz, S., Scheffold, A. Selbstlimitation entzündlicher T-Zell-Antworten. Z. Rheumatol. 67, 500–502 (2008). https://doi.org/10.1007/s00393-008-0343-0

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  • DOI: https://doi.org/10.1007/s00393-008-0343-0

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