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Evidenzbasierte Bewertung der symptomatischen Therapie von Glucosamin

Evidence-based evaluation of study results of symptomatic glucosamine therapy


Meta-Analysen können einen Beitrag zur Evidenz-basierten Medizin liefern. In den zu Glucosamin publizierten systematischen Übersichtsarbeiten wurde die symptomatische Wirksamkeit in der Vergangenheit überwiegend als moderat bis groß beschrieben. Die Ergebnisse der einzelnen klinischen Studien stützten diese Bewertung nicht einheitlich. In den letzten Jahren wurden nun einige neue Studien mit hoher Qualität publiziert. Die aktuelle Studienlage zur symptomatischen Therapie mit Glucosamin bei Patienten mit Gonarthrose wird vorgestellt, gewertet und mit den Ergebnissen der aktuellen Meta-Analysen verglichen.


Meta-analyses can contribute to the field of evidencebased medicine. In the systematic analyses so far published, the symptomatic efficacy of glucosamine was described to be moderate to large. The results of the individual clinical studies however do not support these findings unanimously. In the past couple of years, some new studies of high quality standard were published. This publication gives an overview and an evaluation of the current available studies for the symptomatic treatment of patients with gonarthrosis with glucosamine. It also compares the results of the individual studies with those of recent meta-analyses.

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Reiter, S. Evidenzbasierte Bewertung der symptomatischen Therapie von Glucosamin. Z. Rheumatol. 64, 456–466 (2005).

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  • Glucosamin
  • Kniegelenksarthrose
  • Symptomatische Therapie
  • Meta-Analyse
  • Klinische Studien

Key words

  • Glucosamine
  • knee osteoarthritis
  • symptomatic therapy
  • meta-analysis
  • clinical studies