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Selektive Hemmung der T-Zell-Aktivierung durch das Fusionsprotein CTLA4Ig als neues Therapieprinzip für die RA

Referierte Originalarbeit: Kremer JM, Westhovens R, Leon M, Di Giorgio E, Alten R et al (2003) Treatment of Rheumatoid Arthritis by Selective Inhibiton of T-Cell Activation with Fusion Protein CTLA4Ig. N Engl J Med 349:1907–1915

Selective inhibition of T-cell-activation with fusion protein CTLA4lg—a new treatment option for rheumatoid arthritis

  • KLINISCHE STUDIEN KURZGEFASST
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References

  1. Grohmann U, Orabona C, Fallarino F et al (2002) CTLA-4-Ig regulates tryptophancatabolism in vivo. Nat Immunol 3:1097–1101

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  2. Moreland L, Alten R, van den Bosch F et al (2002) Costimulatory blockade in patients with rheumatoid arthritis: a pilot, dose-finding, double-blind, placebo-controlled clinical trial evaluating CTLA-4Ig and LEA29Y eighty-five days after the first infusion. Arthritis Rheum 46:1470–1479

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  1. St.-Bonifatius-Str. 5, 81541, München, Germany

    K. Krüger

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  1. K. Krüger
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Krüger, K. Selektive Hemmung der T-Zell-Aktivierung durch das Fusionsprotein CTLA4Ig als neues Therapieprinzip für die RA. Z. Rheumatol. 64, 40–41 (2005). https://doi.org/10.1007/s00393-005-0620-0

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  • DOI: https://doi.org/10.1007/s00393-005-0620-0

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