Zusammenfassung.
Azathioprin ist ein in der Rheumatologie seit Jahrzehnten bewährtes, oft verwendetes und sicheres Medikament. Sein Einsatz erfolgt häufig bei Patienten mit Kollagenosen. Diese Patienten zeichnen sich durch Multiorganbefall und eine hohe Rate von Komorbiditäten aus, welche zahlreiche Komedikationen erfordern. Wir berichten über einen Fall von Panzytopenie nach gleichzeitiger Gabe von Azathioprin und Allopurinol bei einer Patientin mit Lupus erythematodes und diabetischer Nephropathie mit Hyperurikämie.
Summary.
Azathioprine has been used in rheumatology for more than twenty years. Indications are collagen diseases with multiorgan involvement, where comedications are frequently necessary. We describe a patient suffering from pancytopenia following a combination therapy of azathioprine and allopurinol because of lupus erythematodes and diabetic nephropathy with hyperuricemia.
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Seidel, W. Panzytopenie unter kombinierter Behandlung mit Azathioprin und Allopurinol. Z Rheumatol 63, 425–427 (2004). https://doi.org/10.1007/s00393-004-0551-1
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DOI: https://doi.org/10.1007/s00393-004-0551-1