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Table 2 Clinical outcomes according to prior CEVD

From: Ten-year all-cause death following percutaneous or surgical revascularization in patients with prior cerebrovascular disease: insights from the SYNTAX Extended Survival study

  Prior CEVD (n = 253) No prior CEVD (n = 1538) HR (95% CI) p value
At 30 days
 MACCE 1.6 (4) 0.6 (9) 1.56 (0.94–2.58) 0.084
 Death, stroke, MI 5.1 (13) 4.1 (63) 1.26 (0.69–2.29) 0.448
 All-cause death 2.4 (6) 1.2 (19) 1.93 (0.77–4.84) 0.159
  Cardiac death 2.4 (6) 1.2 (19) 1.93 (0.77–4.84) 0.159
 Any MI 2.0 (5) 3.3 (50) 0.61 (0.24–1.53) 0.293
 Any stroke 1.2 (3) 0.6 (9) 2.04 (0.55–7.53) 0.285
 Any repeat revascularization 2.8 (7) 2.1 (33) 1.30 (0.58–2.95) 0.522
At 5 years
 MACCE 39.1 (99) 29.9 (460) 1.41 (1.13–1.75) 0.002
 Death, stroke, MI 27.3 (69) 16.7 (257) 1.73 (1.33–2.26)  < 0.001
 All-cause death 19.4 (49) 11.0 (169) 1.88 (1.37–2.58)  < 0.001
  Cardiac death 9.9 (25) 6.3 (97) 1.66 (1.07–2.57) 0.025
 Any MI 7.9 (20) 6.2 (96) 1.32 (0.81–2.13) 0.262
 Any stroke 4.3 (11) 2.6 (40) 1.74 (0.89–3.39) 0.103
 Any repeat revascularization 18.2 (46) 18.6 (286) 1.05 (0.77–1.43) 0.770
At 10 years
 All-cause death 41.1 (100) 24.1 (357) 1.92 (1.54–2.40)  < 0.001
At maximum follow-up
 All-cause death 53.8 (121) 32.5 (442) 1.99 (1.62–2.43)  < 0.001
  1. Data are presented as percentage (number of events). MACCE was defined as a composite of all-cause death, any stroke, any MI, or any revascularization. MACCE major adverse cardiac and cerebrovascular events, MI myocardial infarction