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Recommendations for extracorporeal cardiopulmonary resuscitation (eCPR): consensus statement of DGIIN, DGK, DGTHG, DGfK, DGNI, DGAI, DIVI and GRC

Clinical Research in Cardiology volume 108, pages 455–464 (2019)Cite this article

Abstract

Extracorporeal cardiopulmonary resuscitation (eCPR) may be considered as a rescue attempt for highly selected patients with refractory cardiac arrest and potentially reversible aetiology. Currently, there are no randomised, controlled studies on eCPR. Thus, prospective validated predictors of benefit and outcome are lacking. Currently, selection criteria and procedure techniques differ across hospitals and standardised algorithms are lacking. Based on expert opinion, the present consensus statement provides a first standardised treatment algorithm for eCPR.

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Authors and Affiliations

  1. Department III of Internal Medicine, Heart Centre of the University of Cologne, Kerpener Str. 62, 50937, Cologne, Germany

    Guido Michels & Roman Pfister

  2. Department of Cardiology and Angiology I, Heart Center Freiburg University, Faculty of Medicine, University of Freiburg, Freiburg, Germany

    Tobias Wengenmayer

  3. Department of Cardiac Surgery, Ludwig-Maximilians-University Munich, Munich, Germany

    Christian Hagl & Frank Born

  4. LVR-Hospital Bonn, Bonn, Germany

    Christian Dohmen

  5. Department of Anaesthesiology and Intensive Care Medicine, University Hospital of Cologne, Cologne, Germany

    Bernd W. Böttiger

  6. Department of Cardiology and Angiology, Hannover Medical School, Hannover, Germany

    Johann Bauersachs

  7. Bendorf, Germany

    Andreas Markewitz

  8. Department of Cardiovascular Perfusion, MediClin Heart Center Coswig, Coswig, Saxony-Anhalt, Germany

    Adrian Bauer

  9. Institute for Emergency Medicine, University Hospital Schleswig-Holstein, Kiel, Germany

    Jan-Thorsten Gräsner

  10. Department of Cardiology, Asklepios Klinik St Georg, Hamburg, Germany

    Alexander Ghanem

  11. Department of Emergency Medicine, University Hospital of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany

    Hans-Jörg Busch

  12. Department of Anaesthesiology, Ludwig-Maximilians-University Munich, Munich, Germany

    Uwe Kreimeier

  13. Department of Cardiac Surgery, Heart Centre Duisburg, Evangelisches Krankenhaus Niederrhein, Duisburg, Germany

    Andreas Beckmann

  14. Department of Anaesthesiology, Intensive Care Medicine, Emergency Medicine and Pain Service, Hospital Am Eichert, Alb Fils Kliniken GmbH, Goeppingen, Germany

    Matthias Fischer

  15. Centre of Emergency Medicine, University Hospital Essen, Essen, Germany

    Clemens Kill

  16. Department of Internal Medicine and Intensive Care Medicine, St. Antonius Hospital Eschweiler, Eschweiler, Germany

    Uwe Janssens

  17. Department of Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

    Stefan Kluge

  18. Department of Cardiology and General Internal Medicine, Städtisches Klinikum Solingen gGmbH, Solingen, Germany

    Hans Martin Hoffmeister

  19. Department of Cardiology, Angiology and Pneumology, University of Heidelberg, Heidelberg, Germany

    Michael Preusch

  20. Department of Cardiovascular Surgery, Heinrich Heine University, Düsseldorf, Germany

    Udo Boeken

  21. Department of Internal Medicine, Medical Intensive Care Unit, University of Tuebingen, Tübingen, Germany

    Reimer Riessen

  22. Department of Internal Medicine/Cardiology, Heart Center Leipzig, University Hospital, Leipzig, Germany

    Holger Thiele

  23. German Society of Medical Intensive Care and Emergency Medicine (Deutsche Gesellschaft für Internistische Intensivmedizin und Notfallmedizin, DGIIN), Berlin, Germany

    Guido Michels, Tobias Wengenmayer, Hans-Jörg Busch, Uwe Janssens, Stefan Kluge & Reimer Riessen

  24. German Society of Thoracic, Cardiac and Vascular Surgery (Deutsche Gesellschaft für Thorax-, Herz- und Gefäßchirurgie, DGTHG), Berlin, Germany

    Christian Hagl, Andreas Markewitz & Andreas Beckmann

  25. German Society of Neuro-Intensive Care and Emergency Medicine (Deutsche Gesellschaft für Neurointensiv- und Notfallmedizin, DGNI), Jena, Germany

    Christian Dohmen

  26. German Interdisciplinary Association for Intensive Care and Emergency Medicine (Deutsche Interdisziplinäre Vereinigung für Intensiv- und Notfallmedizin, DIVI), Berlin, Germany

    Christian Dohmen, Bernd W. Böttiger, Andreas Markewitz, Hans-Jörg Busch, Uwe Kreimeier, Uwe Janssens & Stefan Kluge

  27. German Society of Anaesthesiology and Intensive Care Medicine (Deutsche Gesellschaft für Anästhesiologie und Intensivmedizin, DGAI), Nürnberg, Germany

    Bernd W. Böttiger, Jan-Thorsten Gräsner, Matthias Fischer & Clemens Kill

  28. German Resuscitation Council (GRC), Ulm, Germany

    Bernd W. Böttiger, Jan-Thorsten Gräsner, Hans-Jörg Busch & Uwe Kreimeier

  29. German Cardiac Society (Deutsche Gesellschaft für Kardiologie, DGK), Düsseldorf, Germany

    Johann Bauersachs, Hans Martin Hoffmeister & Holger Thiele

  30. German Society of Cardiotechnics (Deutsche Gesellschaft für Kardiotechnik, DGfK), Coswig, Saxony-Anhalt, Germany

    Adrian Bauer & Frank Born

Authors
  1. Guido Michels
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  2. Tobias Wengenmayer
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  3. Christian Hagl
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  4. Christian Dohmen
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  5. Bernd W. Böttiger
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  6. Johann Bauersachs
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  7. Andreas Markewitz
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  8. Adrian Bauer
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  9. Jan-Thorsten Gräsner
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  10. Roman Pfister
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  11. Alexander Ghanem
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  12. Hans-Jörg Busch
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  13. Uwe Kreimeier
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  14. Andreas Beckmann
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  15. Matthias Fischer
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  16. Clemens Kill
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  17. Uwe Janssens
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  18. Stefan Kluge
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  19. Frank Born
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  20. Hans Martin Hoffmeister
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  21. Michael Preusch
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  22. Udo Boeken
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  23. Reimer Riessen
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  24. Holger Thiele
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Correspondence to Guido Michels.

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Michels G is a member of the scientific advisory board of the German Society of Medical Intensive Care and Emergency Medicine (Deutsche Gesellschaft für Internistische Intensivmedizin und Notfallmedizin, DGIIN), commissionery leader of the working group of “Cardiopulmonary Resuscitation” of the German Society for Cardiology (Deutsche Gesellschaft für Kardiologie, DGK) and member of the working group “ECMO / eCPR” of the German Resuscitation Council (GRC) and received lecture fees from Pfizer, Novartis, Servier, ZOLL and Orion Pharma. Bauersachs J is the leader of the DFG-funded Clinical Research Group (KFO) 311 “(Pre) terminal heart and lung failure: Relief and Repair” and received lecture fees and research support from Abiomed and ZOLL. Böttiger BW is European Resuscitation Council (ERC) Board Director Science and Research, chairman of the German Resuscitation Council (GRC), member of the “Advanced Cardiac Life Support” (ALS) Task Force of the International Liaison Committee on Resuscitation (ILCOR), member of the presidium of the German Interdisciplinary Association for Intensive Care and Emergency Medicine (Deutsche Interdisziplinäre Vereinigung für Intensiv- und Notfallmedizin, DIVI), associated editor of the European Journal of Anaesthesiology (EJA), co-editor of the journal Resuscitation, editor of the journal Notfall + Rettungsmedizin. For lectures he has received fees from the following companies: Medupdate, Forum for Medical Education (FoMF), Baxalta, Bayer Vita, ZOLL, BARD. Ghanem A has received lecture fees from Getinge. Markewitz A received a lecture fee from TÜV Süd, München. Gräsner JT is the leader of the scientific working group “emergency medicine” of the German Society of Anaesthesiology and Intensive Care Medicine (Deutsche Gesellschaft für Anästhesiologie und Intensivmedizin, DGAI), speaker of the organizing committee of the “German Reanimation Registry”, Chair of the European Registry of Cardiac Arrest, member of the executive committee of the German Council for Resuscitation (GRC), member of the presidium of the professional association of german anaesthesiologists. Kreimeier U is leader of the working group “Advanced Life Support” at the German Resuscitation Council (GRC). Wengenmayer T, Hagl C, Dohmen C, Bauer A, Pfister R, Busch HJ, Beckmann A, Fischer M, Kill C, Janssens U, Kluge S, Born F, Hoffmeister HM, Preusch M, Boeken U, Riessen R and Thiele H declare, that there is no conflict of interest with respect to the subject publication.

Additional information

This consensus statement was also published in Medizinische Klinik—Intensivmedizin und Notfallmedizin, Der Kardiologe, Der Anaesthesist, Zeitschrift für Herz-, Thorax- und Gefäßchirurgie und Anästhesiologie and Intensivmedizin. The consensus paper is currently available in German only. This paper is the first English version of the eCPR German consensus statement.

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Michels, G., Wengenmayer, T., Hagl, C. et al. Recommendations for extracorporeal cardiopulmonary resuscitation (eCPR): consensus statement of DGIIN, DGK, DGTHG, DGfK, DGNI, DGAI, DIVI and GRC. Clin Res Cardiol 108, 455–464 (2019). https://doi.org/10.1007/s00392-018-1366-4

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  • DOI: https://doi.org/10.1007/s00392-018-1366-4

Keywords

  • Cardiac arrest
  • Extracorporeal cardiopulmonary resuscitation
  • Extracorporeal membrane oxygenation
  • Cardiogenic shock
  • Resuscitation