Skip to main content
Log in

Catheter ablation of pediatric AV nodal reentrant tachycardia: results in small children

  • Original Paper
  • Published:
Clinical Research in Cardiology Aims and scope Submit manuscript

Abstract

Background

AV nodal reentrant tachycardia (AVNRT) is commonly encountered in pediatric patients. Definite treatment can be achieved by catheter ablation. The purpose of the study was to evaluate the efficacy and safety of AVNRT ablation focusing on children with a body weight ≤25 kg.

Patients and results

Catheter ablation of AVNRT was attempted in 253 patients. Median age was 12.5 years; median body weight was 48.7 kg. 25 (9.9 %) children had a body weight ≤25 kg. Congenital heart disease was present in 6 patients (2.4 %). Procedural success was achieved in 98 % using radiofrequency, in 100 % using cryoenergy alone, and in 94 % using both energy sources. In patients with a body weight ≤25 kg, success was achieved in 96 %. In patients ≤25 kg, fluoroscopy and procedure duration did not differ from those >25 kg. The rate of major complications was significantly higher in the patients ≤25 kg (12 vs. 2.2 %, p = 0.04). Permanent AV block after RF ablation occurred in 2 patients with congenital heart disease and one infant with a body weight of 8.7 kg.

Conclusions

Catheter ablation of AVNRT in children and adolescents was safe and effective. Infants and small children with a body weight ≤25 kg had a higher prevalence of serious complications. This should alert physicians in decision making toward catheter ablation in these patients. In patients with congenital heart disease and different anatomy of the cardiac conduction system, operators must be aware of an increased risk for AV block.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Kugler JD, Danford DA, Houston KA, Felix G, Pediatric Radiofrequency Ablation Registry of the Pediatric Radiofrequency Ablation Registry of the Pediatric Electrophysiology S (2002) Pediatric radiofrequency catheter ablation registry success, fluoroscopy time, and complication rate for supraventricular tachycardia: comparison of early and recent eras. J Cardiovasc Electrophysiol 13:336–341

    Article  PubMed  Google Scholar 

  2. Van Hare GF, Javitz H, Carmelli D, Saul JP, Tanel RE, Fischbach PS, Kanter RJ, Schaffer M, Dunnigan A, Colan S, Serwer G (2004) Prospective assessment after pediatric cardiac ablation: demographics, medical profiles, and initial outcomes. J Cardiovasc Electrophysiol 15:759–770

    Article  PubMed  Google Scholar 

  3. Kriebel T, Broistedt C, Kroll M, Sigler M, Paul T (2005) Efficacy and safety of cryoenergy in the ablation of atrioventricular reentrant tachycardia substrates in children and adolescents. J Cardiovasc Electrophysiol 16:960–966

    Article  PubMed  Google Scholar 

  4. Kubus P, Vit P, Gebauer RA, Zaoral L, Peichl P, Fiala M, Janousek J (2014) Long-term results of paediatric radiofrequency catheter ablation: a population-based study. Europace 16:1808–1813

    Article  PubMed  Google Scholar 

  5. Kugler JD, Danford DA, Houston K, Felix G (1997) Radiofrequency catheter ablation for paroxysmal supraventricular tachycardia in children and adolescents without structural heart disease. Pediatric EP Society, Radiofrequency Catheter Ablation Registry. Am J Cardiol 80:1438–1443

    Article  CAS  PubMed  Google Scholar 

  6. Kugler JD, Danford DA, Deal BJ, Gillette PC, Perry JC, Silka MJ, Van Hare GF, Walsh EP (1994) Radiofrequency catheter ablation for tachyarrhythmias in children and adolescents. The Pediatric Electrophysiology Society. N Engl J Med 330:1481–1487

    Article  CAS  PubMed  Google Scholar 

  7. Ko JK, Deal BJ, Strasburger JF, Benson DW Jr (1992) Supraventricular tachycardia mechanisms and their age distribution in pediatric patients. Am J Cardiol 69:1028–1032

    Article  CAS  PubMed  Google Scholar 

  8. LaPage MJ, Reed JH, Collins KK, Law IH, Pilcher TA, Tanel RE, Anderson CC, Young ML, Emmel M, Paul T, Blaufox AD, Arora G, Saul JP (2011) Safety and results of cryoablation in patients <5 years old and/or <15 kilograms. Am J Cardiol 108:565–571

    Article  PubMed  Google Scholar 

  9. Blaufox AD, Saul JP (2004) Acute coronary artery stenosis during slow pathway ablation for atrioventricular nodal reentrant tachycardia in a child. J Cardiovasc Electrophysiol 15:97–100

    Article  PubMed  Google Scholar 

  10. Schneider HE, Kriebel T, Gravenhorst VD, Paul T (2009) Incidence of coronary artery injury immediately after catheter ablation for supraventricular tachycardias in infants and children. Heart Rhythm 6:461–467

    Article  PubMed  Google Scholar 

  11. Denes P, Wu D, Dhingra R, Amat-y-Leon F, Wyndham C, Rosen KM (1975) Dual atrioventricular nodal pathways. A common electrophysiological response. Brit Heart J 37:1069–1076

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  12. Bertram H, Windhagen-Mahnert B, Bokenkamp R, Kriebel T, Peuster M, Hausdorf G, Paul T (2001) Abbreviated combined anatomical/electrophysiological approach for catheter ablation of atrioventricular nodal reentrant tachycardia in children. Cardiol Young 11:182–187

    Article  CAS  PubMed  Google Scholar 

  13. Jackman WM, Beckman KJ, McClelland JH, Wang X, Friday KJ, Roman CA, Moulton KP, Twidale N, Hazlitt HA, Prior MI et al (1992) Treatment of supraventricular tachycardia due to atrioventricular nodal reentry, by radiofrequency catheter ablation of slow-pathway conduction. N Engl J Med 327:313–318

    Article  CAS  PubMed  Google Scholar 

  14. Manolis AS, Wang PJ, Estes NA 3rd (1994) Radiofrequency ablation of slow pathway in patients with atrioventricular nodal reentrant tachycardia. do arrhythmia recurrences correlate with persistent slow pathway conduction or site of successful ablation? Circulation 90:2815–2819

    Article  CAS  PubMed  Google Scholar 

  15. Feldman A, Voskoboinik A, Kumar S, Spence S, Morton JB, Kistler PM, Sparks PB, Vohra JK, Kalman JM (2011) Predictors of acute and long-term success of slow pathway ablation for atrioventricular nodal reentrant tachycardia: a single center series of 1,419 consecutive patients. Pacing Clin Electrophysiol 34:927–933

    Article  PubMed  Google Scholar 

  16. Lee PC, Hwang B, Chen SA, Tai CG, Chen YJ, Chiang CE, Meng CC (2007) The results of radiofrequency catheter ablation of supraventricular tachycardia in children. Pacing Clin Electrophysiol 30:655–661

    Article  PubMed  Google Scholar 

  17. Joung B, Lee M, Sung JH, Kim JY, Ahn S, Kim S (2006) Pediatric radiofrequency catheter ablation: sedation methods and success, complication and recurrence rates. Circ J 70:278–284

    Article  PubMed  Google Scholar 

  18. Brugada J, Blom N, Sarquella-Brugada G, Blomstrom-Lundqvist C, Deanfield J, Janousek J, Abrams D, Bauersfeld U, Brugada R, Drago F, de Groot N, Happonen JM, Hebe J, Yen Ho S, Marijon E, Paul T, Pfammatter JP, Rosenthal E, European Heart Rhythm A, Association for European P, Congenital C (2013) Pharmacological and non-pharmacological therapy for arrhythmias in the pediatric population: EHRA and AEPC-Arrhythmia Working Group joint consensus statement. Europace 15:1337–1382

    Article  PubMed  Google Scholar 

  19. Crosson JE, Hesslein PS, Thilenius OG, Dunnigan A (1995) Av node reentry tachycardia in infants. Pacing Clin Electrophysiol 18:2144–2149

    Article  CAS  PubMed  Google Scholar 

  20. Kriebel T, Bertram H, Windhagen-Mahnert B, Bokenkamp R, Kaulitz R, Rohloff A, Peuster M, Hausdorf G, Paul T (2000) atrioventricular nodal reentry tachycardia in children: curative treatment by high frequency catheter ablation. Z Kardiol 89:538–545

    Article  CAS  PubMed  Google Scholar 

  21. Miyake CY, Mah DY, Atallah J, Oikle HP, Melgar ML, Alexander ME, Berul CI, Cecchin F, Walsh EP, Triedman JK (2011) Nonfluoroscopic imaging systems reduce radiation exposure in children undergoing ablation of supraventricular tachycardia. Heart Rhythm 8:519–525

    Article  PubMed  Google Scholar 

  22. Mah DY, Miyake CY, Sherwin ED, Walsh A, Anderson MJ, Western K, Abrams DJ, Alexander ME, Cecchin F, Walsh EP, Triedman JK (2014) The use of an integrated electroanatomic mapping system and intracardiac echocardiography to reduce radiation exposure in children and young adults undergoing ablation of supraventricular tachycardia. Europace 16:277–283

    Article  PubMed  Google Scholar 

  23. Reithmann C, Fiek M (2014) Fast pathway ablation for atrioventricular nodal reentrant tachycardia with a marked pr interval prolongation during sinus rhythm following transcatheter aortic valve implantation. Clin Res Cardiol 103:495–498

    Article  PubMed  Google Scholar 

  24. Aiyagari R, Saarel EV, Etheridge SP, Bradley DJ, Dick M 2nd, Fischbach PS (2005) Radiofrequency Ablation for Supraventricular Tachycardia in Children < or = 15 Kg Is Safe and Effective. Pediatr Cardiol 26:622–626

    Article  CAS  PubMed  Google Scholar 

Download references

Conflict of interest

The authors have no conflicts of interest to disclose.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Ulrich Krause.

Additional information

U. Krause and D. Backhoff contributed equally to this work.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Krause, U., Backhoff, D., Klehs, S. et al. Catheter ablation of pediatric AV nodal reentrant tachycardia: results in small children. Clin Res Cardiol 104, 990–997 (2015). https://doi.org/10.1007/s00392-015-0868-6

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00392-015-0868-6

Keywords

Navigation