Skip to main content

Advertisement

SpringerLink
Log in

Long-term survival in a patient with AL amyloidosis after cardiac transplantation followed by autologous stem cell transplantation

  • CLINICAL CORRESPONDENCE
  • Published:
Clinical Research in Cardiology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Alloni A, Pellegrini C, Ragni T, Goggi C, D’Armini AM, Rinaldi M, Vigano M (2004) Heart transplantation in patients with amyloidosis: single-center experience. Transplant Proc 36:643– 644

    Article  PubMed  CAS  Google Scholar 

  2. Comenzo RL, Vosburgh E, Falk RH, Sanchorawala V, Reisinger J, Dubrey S, Dember LM, Berk JL, Akpek G, La- Valley M, O’Hara C, Arkin CF, Wright DG, Skinner M (1998) Dose-intensive melphalan with blood stem-cell support for the treatment ao AL (amyloid light-chain) amyloidosis: survival and responses in 25 patients. Blood 91:3662–3670

    PubMed  CAS  Google Scholar 

  3. Comenzo RL, Gertz MA (2002) Autologous stem cell transplantation for primary systemic amyloidosis. Blood 99:4276–4282

    Article  PubMed  CAS  Google Scholar 

  4. Dubrey SW, Burke MM, Hawkins PN, Banner NR (2004) Cardiac transplantation for amyloid heart disease: the United Kingdom experience. J Heart Lung Transplant 23:1142–1153

    Article  PubMed  Google Scholar 

  5. Falk RH, Comenzo RL, Skinner M (1997) The systemic amyloidosis. N Engl J Med 337:898–909

    Article  PubMed  CAS  Google Scholar 

  6. Gertz MA, Lacy MQ, Dispenzieri A, Gastineau DA, Chen MG, Ansell SM, Inwards DJ, Micallef IN, Tefferi A, Litzow MR (2002) Stem cell transplantation for the management of primary systemic amyloidosis. Am J M 113:549–555

    Article  CAS  Google Scholar 

  7. Gillmore JD, Goodman HJ, Lachmann HJ, Offer M, Wechalekar AD, Joshi J, Pepys MB, Hawkins PN (2006) Sequential cardiac and autologous stem cell transplantation for systemic AL amyloidosis. Blood 107:1227–1229

    Article  PubMed  CAS  Google Scholar 

  8. Hosenpud JD, DeMarco T, Frazier OH, Griffith BP, Uretsky BF, Menkis AH, O’Connell JB, Olivari MT, Valantine HA (1991) Progression of systemic disease and reduced long-term survival in patients with cardiac amyloidosis undergoing heart transplantation. Follow-up results of a multicenter survey. Circulation 84:338–343

    Google Scholar 

  9. Hawkins PN, Lavender JP, Pepys MB (1990) Evaluation of systemic amyloidosis by scintigraphy with 123I-labeled serum amyloid P component. N Engl J Med 323:542–543

    Article  Google Scholar 

  10. Kyle RA, Gertz MA, Greipp PR, Witzig TE, Lust JA, Lacy MQ, Therneau TM (1999) Long-term survival (10 years or more) in 30 patients with primary amyloidosis. Blood 93:1062–1066

    PubMed  CAS  Google Scholar 

  11. Mohty M, Albat B, Fegueux N, Rossi JF (2001) Autologous peripheral blood stem cell transplantation following heart transplantation for primary systemic amyloidosis. Leuk Lymph 41:221–223

    Article  CAS  Google Scholar 

  12. Perz JB, Schonland SO, Hundemer M, Kristen AV, Dengler TJ, Zeier M, Linke RP, Ho AD, Goldschmidt H (2004) High-dose melphalan with autologous stem cell transplantation after VAD induction chemotherapy for treatment of AL amyloidosis: a single centre prospective phase II study. Br J Haematol 127:543–551

    Article  PubMed  CAS  Google Scholar 

  13. Skinner M, Sanchorawala V, Seldin DC, Dember LM, Falk RH, Berk JL, Anderson JJ, O’Hara C, Finn KT, Libbey CA, Wiesman J, Quillen K, Swan N, Wright DG (2004) High-dose melphalan and autologous stem-cell transplantation in patients with AL amyloidosis: an 8-year study. Ann Int Med 140:85–93

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Abteilung für Hämatologie, Medizinische Klinik V, Universitätsklinikum Heidelberg, INF 410, 69120, Heidelberg, Germany

    Jolanta B. Perz & Falk-Udo Sack

  2. Department of Haematology, Hammersmith Hospital, London, UK

    Jolanta B. Perz, Amin Rahemtulla & Jane F. Apperley

  3. Transplant Unit, Cambridge University Papworth Hospital, Cambridge, UK

    Jayan Parameshwar

  4. Department of Cardiology, University Hospital Heidelberg, Heidelberg, Germany

    Arnt V. Kristen, Hugo A. Katus & Thomas J. Dengler

  5. Department of Haematology, University Hospital Heidelberg, Heidelberg, Germany

    Jolanta B. Perz & Hartmut Goldschmidt

Authors
  1. Jolanta B. Perz
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Arnt V. Kristen
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Amin Rahemtulla
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Jayan Parameshwar
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Falk-Udo Sack
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Jane F. Apperley
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Hartmut Goldschmidt
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Hugo A. Katus
    View author publications

    You can also search for this author in PubMed Google Scholar

  9. Thomas J. Dengler
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Jolanta B. Perz.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Perz, J.B., Kristen, A.V., Rahemtulla, A. et al. Long-term survival in a patient with AL amyloidosis after cardiac transplantation followed by autologous stem cell transplantation. Clin Res Cardiol 95, 671–674 (2006). https://doi.org/10.1007/s00392-006-0439-y

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00392-006-0439-y

Keywords

Search

Navigation