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Assessment of shunt volumes in children with ventricular septal defects:

comparative quantification of MR flow measurements and invasive oximetry

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Summary

The aim of this study was to compare the results of magnetic resonance based shunt volume measurements with the results of the invasive method by the principle of Fick. In 14 children (median age: 16.5 months) with ventricular septal defects the shunt volume was quantified by magnetic resonance flow measurements under spontaneous breathing conditions as well as with invasive angiography during one sedation. A good correlation between both methods was observed (r2 = 0.8, p <0.0001, CI95% = 0.62–1.22). A tendency towards higher values in the noninvasive technique was found in the Bland-Altman plot (bias = 3.79). Magnetic resonance based shunt measurements are a reliable alternative to the invasive shunt measurement by cardiac catheterization.

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Authors and Affiliations

  1. OncoRay – Molecular Imaging, Medical Faculty of Carl Gustav Carus, Technical University Dresden, Fetscherstraße 74, P.O. Box 86, 01307, Dresden, Germany

    Arne Koch & Nasreddin Abolmaali MD

  2. Department of Pediatric Cardiology, Johann Wolfgang Goethe University, Hospital, Frankfurt/M, Germany

    Anoosh Esmaeili, Rene Höhn & Roland Hofstetter

  3. Institute for Diagnostic and Interventional Radiology, Johann Wolfgang Goethe University, Hospital, Frankfurt/M, Germany

    Thomas Josef Vogl

Authors
  1. Anoosh Esmaeili
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  2. Rene Höhn
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  3. Arne Koch
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  4. Thomas Josef Vogl
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  5. Roland Hofstetter
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  6. Nasreddin Abolmaali MD
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Correspondence to Nasreddin Abolmaali MD.

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Esmaeili, A., Höhn, R., Koch, A. et al. Assessment of shunt volumes in children with ventricular septal defects:. Clin Res Cardiol 95, 523–530 (2006). https://doi.org/10.1007/s00392-006-0415-6

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  • DOI: https://doi.org/10.1007/s00392-006-0415-6

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