Summary
Myocardial perfusion imaging enables not only accurate diagnosis of disease but also entails prognostic value. Myocardial perfusion SPECT contributes to assessment of future cardiac events independently of other clinical parameters. A normal stress myocardial perfusion scan is associated with a favorable prognosis independent of history, symptoms, and exercise electrocardiography test variables. Cardiac risk and benefit from invasive therapeutic strategies increase in relation to the severity of the abnormality of perfusion and function assessed by gated myocardial perfusion SPECT. Thus, stress myocardial perfusion imaging may serve as a gatekeeper for referral to coronary angiography enabling effective risk stratification in patients with suspected or documented coronary artery disease.
Zusammenfassung
Die Aussagen der Myokardperfusions-SPECT enthalten ergänzend zur diagnostischen Wertigkeit auch eine prognostische Information. Sie gestatten eine Abschätzung der zukünftigen kardialen Ereignisrate unabhängig von weiteren klinischen Parametern. Ein Normalbefund in der Belastungsmyokardperfusions-SPECT ist unabhängig von anamnestischen, klinischen und ergometrischen Daten mit einer guten Prognose verbunden. Mit zunehmendem Ausmaß von Perfusionsdefekten und Funktionsstörungen in der herzphasengetriggert-akquirierten Myokardperfusions-SPECT (Gated-SPECT) steigt das Risiko zukünftiger kardialer Ereignisse und somit der Zugewinn durch eine invasive Therapiestrategie an. Mit der Gated-SPECT als „Gatekeeper“ für die Überweisung zur Koronarangiographie gelingt eine effiziente Risikostratifizierung von Patienten mit vermuteter oder chronischer koronarer Herzerkrankung.
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Nowak, B. Stellenwert der Gated-SPECT-Myokardperfusionsszintigraphie zur Beurteilung des individuellen kardialen Risikos. ZS Kardiologie 94 (Suppl 4), iv81–iv84 (2005). https://doi.org/10.1007/s00392-005-1417-5
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DOI: https://doi.org/10.1007/s00392-005-1417-5