Zusammenfassung
Das Angiosarkom ist der häufigste primäre maligne Tumor des Herzens im Erwachsenenalter mit einer schlechten Prognose. Die Krankheitszeichen sind meist unspezifisch, so dass die Diagnose oft mit Verzögerung erfolgt. Die Symptome werden durch Größe und Lage des Tumors bestimmt. Die Echokardiographie ist aufgrund der Präzision, fehlenden Invasivität und Kosteneffektivität die primäre Untersuchungsmethode. Eine verbesserte Überlebensrate wird nur durch eine vollständige chirurgische Resektion erreicht. Der natürliche Krankheitsverlauf wird durch eine postoperative Chemotherapie nicht verändert. Im nachfolgenden Fallbeispiel wird ein großes Angiosarkom mit Infiltration der rechten Vorhof- und Ventrikelwand beschrieben und ein kritischer Überblick über die aktuelle Literatur geboten.
Summary
Angiosarcoma of the heart, the most common primary malignant cardiac tumor in adults is known to carry a dismal prognosis. The diagnosis is often delayed because of the nonspecific clinical presentation. Symptoms are determined by the size and location of the tumor. Echocardiography has become the primary diagnostic technique because of its high degree of accuracy, noninvasiveness, and cost effectiveness. Complete surgical resection is required for improved survival. Conventional postoperative chemotherapy does not appear to modify the clinical course. We report a case of cardiac angiosarcoma with a large mural mass infiltrating the right atrial and ventricular walls and critically review the pertinent literature.
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Brandt, R.R., Arnold, R., Bohle, R.M. et al. Cardiac angiosarcoma: case report and review of the literature. ZS Kardiologie 94, 824–828 (2005). https://doi.org/10.1007/s00392-005-0296-0
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DOI: https://doi.org/10.1007/s00392-005-0296-0