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Empfehlungen für die Sekundärprävention nach Myokardinfarkt

Recommendations for secondary prevention after myocardial infarction

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Summary.

The new ESC guidelines for secondary prevention after STEMI recommend acetylsalicylic acid, betablockers, ACE inhibitors, statins and as a new therapeutic option 1 g n-3-fatty acids. They also advocate strict control of elevated blood pressure and plasma glucose level. To stop smoking remains obligatory, supplemented by the advice to adhere to a mediterranean diet. The clinical value of using 1 g n-3-fatty acids was shown in the GISSI-P trial and seem to reduce especially arrhythmic events. Considering the number needed to treat for the different pharmacologic therapies, betablockers and ACE inhibitors are essentials if not contraindicated, n-3-fatty acids and statins show each comparable efficacy while acetylsalicylic acid still provides a good cost/benefit relation due to its low price.

Zusammenfassung.

Die neuen Leitlinien der ESC zur Sekundärprävention nach ST-Hebungsinfarkt ergänzen die etablierten Therapeutika ASS, Betablocker, ACE-Hemmer und Statine um hochkonzentrierte Omega-3-Fettsäuren. Zu den empfohlenen Allgemeinmaßnahmen ist neben dem Rauchverzicht und einer optimalen Blutdruck- und Blutzuckereinstellung die mediterrane Kost getreten. Allgemeinmaßnahmen haben ihren eigenen Stellenwert und sollten immer unabhängig von der gewählten medikamentösen Therapie angestrebt werden.

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Arntz, HR. Empfehlungen für die Sekundärprävention nach Myokardinfarkt. Z Kardiol 93 (Suppl 1), i23–i25 (2004). https://doi.org/10.1007/s00392-004-1108-7

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  • DOI: https://doi.org/10.1007/s00392-004-1108-7

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