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Osteoporose und Multimorbidität

Osteoporosis and multimorbidity

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Zusammenfassung

Osteoporose ist eine systemische Knochenerkrankung, die durch verminderte Knochenfestigkeit zu einem erhöhten Frakturrisiko prädisponiert. Gerade ältere Patienten weisen ein hohes Risiko für Fragilitätsfrakturen auf. Bei diesen Patienten reicht die isolierte Betrachtung der Osteoporose nicht aus; vielmehr sollte diese im Kontext der Multimorbidität gesehen werden. Verschiedene Erkrankungen sind mit Osteoporose assoziiert, sei es durch pathophysiologische Mechanismen, gemeinsame Risikofaktoren oder aufgrund ihrer pharmakologischen Therapie. Auch geriatrische Syndrome wie etwa Sturzneigung spielen eine wesentliche Rolle. Dieser Beitrag gibt einen Überblick über Multimorbiditätsinteraktionen anhand ausgewählter häufiger Erkrankungen im höheren Lebensalter und zeigt das Vorgehen in der klinischen Praxis.

Abstract

Osteoporosis is a systemic bone disease with decreased bone strength and mass resulting in an increased predisposition to fracture risk. Especially older patients have a high risk for fragility fractures. In these patients an isolated view of osteoporosis without consideration of multimorbidity is insufficient. Various diseases are associated with osteoporosis because of shared pathophysiological mechanisms, risk factors or as a consequence of medication. Furthermore, geriatric syndromes, such as falls play an importance role. This article presents an overview about multimorbidity interactions based on selected frequent diseases in older age and shows the management in the clinical practice.

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  1. Medizinische Klinik 2 – Schwerpunkt Geriatrie, Universitätsklinik für Geriatrie, Paracelsus Medizinische Privatuniversität, Campus Nürnberg, Prof.-Ernst-Nathan-Str. 1, 90419, Nürnberg, Deutschland

    S. Wicklein & M. Gosch

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S. Wicklein und M. Gosch geben an, dass kein Interessenkonflikt besteht.

Für diesen Beitrag wurden von den Autoren keine Studien an Menschen oder Tieren durchgeführt. Für die aufgeführten Studien gelten die jeweils dort angegebenen ethischen Richtlinien.

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Wicklein, S., Gosch, M. Osteoporose und Multimorbidität. Z Gerontol Geriat 52, 433–439 (2019). https://doi.org/10.1007/s00391-019-01569-5

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