Zusammenfassung
Hintergrund
Notaufnahmen werden zunehmend mit multimorbiden und komplex zu versorgenden älteren Patienten konfrontiert. Infektionen stellen eine der Haupttodesursachen der älteren Patienten, die sich in einer Notaufnahme vorstellen, dar. Sie sind aber häufig nur schwierig bei den betroffenen Patienten zu diagnostizieren.
Ziel der Arbeit
Die vorliegende Arbeit bietet eine Übersicht über wichtige Befundkonstellationen und Möglichkeiten/Limitierungen der Diagnostik von Infektionen bei älteren Patienten.
Material und Methode
Hierzu wurde eine selektive Literaturrecherche in PubMed im Zeitraum zwischen 1990 und 2015 durchgeführt. Ergänzend werden eigene Daten vorgestellt.
Ergebnisse und Schlussfolgerung
Infektionen älterer Notfallpatienten präsentieren sich häufig atypisch; daher ist es notwendig, auch subtile Veränderungen zu berücksichtigen. Zur Diagnosestellung einer akuten Infektion sind unspezifische Symptome, Vitalparameter, Laborwerte (einschließlich Infektionsmarker wie C-reaktives Protein oder Prokalzitonin), der kognitive Status und die Funktionalität des Patienten zu berücksichtigen.
Abstract
Background
Elderly patients represent an increasing population in the emergency department (ED) and physicians often have to deal with multimorbidity and complexity. Infections are one of the major reasons for ED presentations of older patients and the main cause of mortality; however, infections are often difficult to diagnose in older patients.
Aim
This article provides a review of important indicators for infections, diagnostic tools and limitations in elderly patients.
Material and methods
A literature search was carried out using PubMed in the period 1990–2015 and in addition own published data are presented.
Results and conclusion
Infections in the elderly are difficult to assess in the emergency department due to atypical symptoms. Even subtle changes need to be recognized. For the diagnosis of infections in older ED patients unspecific symptoms, vital parameters, laboratory parameters, including C-reactive protein (CRP) and procalcitonin levels, cognitive function and functionality of the patient need to be taken into account.
Literatur
Ahkee S, Srinath L, Ramirez J (1997) Community-acquired pneumonia in the elderly: association of mortality with lack of fever and leukocytosis. South Med J 90:296–298
Apa (2000) Task force on DSM-IV: diagnostic and statistial manual of mental disorders: DSM-IV-TR, 4. Aufl. American Psychiatric Association, Wachington, DC
Bhalla MC, Wilber ST, Stiffler KA et al (2014) Weakness and fatigue in older ED patients in the United States. Am J Emerg Med 32(11):1395–1398
Christ M, Dodt C, Geldner G et al (2010) [Presence and future of emergency medicine in Germany]. Anasthesiol Intensivmed Notfallmed Schmerzther 45:666–671
Christ M, Grossmann F, Winter D et al (2010) Modern triage in the emergency department. Dtsch Arztebl Int 107:892–898
Christ M, Popp S, Erbguth E (2010) Algorithmen zur Abklärung von Bewusstseinsstörungen in der Notaufnahme. Intensivmed Notfallmed 47:83inf
Delerme S, Ray P (2008) Acute respiratory failure in the elderly: diagnosis and prognosis. Age Ageing 37:251–257
Dellinger RP, Levy MM, Rhodes A et al (2013) Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock, 2012. Intensive Care Med 39:165–228
Drewes YM, Den Elzen WP, Mooijaart SP et al (2011) The effect of cognitive impairment on the predictive value of multimorbidity for the increase in disability in the oldest old: the Leiden 85-plus Study. Age Ageing 40:352–357
Eriksson I, Gustafson Y, Fagerstrom L et al (2011) Urinary tract infection in very old women is associated with delirium. Int Psychogeriatr 23:496–502
Grief CL (2003) Patterns of ED use and perceptions of the elderly regarding their emergency care: a synthesis of recent research. J Emerg Nurs 29:122–126
Grossmann FF, Hasemann W, Graber A et al (2014) Screening, detection and management of delirium in the emergency department – a pilot study on the feasibility of a new algorithm for use in older emergency department patients: the modified Confusion Assessment Method for the Emergency Department (mCAM-ED). Scand J Trauma Resusc Emerg Med 22:19
Grossmann FF, Zumbrunn T, Ciprian S et al (2014) Undertriage in older emergency department patients–tilting against windmills? PLoS One 9:e106203
Gyetko MR, Toews GB (1993) Immunology of the aging lung. Clin Chest Med 14:379–391
Heppner HJ, Bertsch T, Alber B et al (2010) Procalcitonin: inflammatory biomarker for assessing the severity of community-acquired pneumonia–a clinical observation in geriatric patients. Gerontology 56:385–389
Heppner HJ, Cornel S, Peter W et al (2013) Infections in the elderly. Crit Care Clin 29:757–774
Heppner Hj, Singler K, Kwetkat A et al (2012) Do clinical guidelines improve management of sepsis in critically ill elderly patients? A before-and-after study of the implementation of a sepsis protocol. Wien Klin Wochenschr 124:692–698
Hoffken G, Lorenz J, Kern W et al (2010) Guidelines of the Paul-Ehrlich-Society of Chemotherapy, the German Respiratory Diseases Society, the German Infectious Diseases Society and of the Competence Network CAPNETZ for the Management of Lower Respiratory Tract Infections and Community-acquired Pneumonia. Pneumologie 64:149–154
Hogan TM, Losman ED, Carpenter CR et al (2010) Development of geriatric competencies for emergency medicine residents using an expert consensus process. Acad Emerg Med 17:316–324
Horattas MC, Guyton DP, Wu D (1990) A reappraisal of appendicitis in the elderly. Am J Surg 160:291–293
Hortmann M, Heppner HJ, Popp S et al (2014) Reduction of mortality in community-acquired pneumonia after implementing standardized care bundles in the emergency department. Eur J Emerg Med 21:429–435
Hortmann M, Heppner HJ, Singler K et al (2015) [Community acquired pneumonia in the emergence department – do standardized care bundles improve quality of care?]. Anasthesiol Intensivmed Notfallmed Schmerzther 50:92–101
Kothe H, Bauer T, Marre R et al (2008) Outcome of community-acquired pneumonia: influence of age, residence status and antimicrobial treatment. Eur Respir J 32:139–146
Lamantia MA, Messina FC, Hobgood CD et al (2014) Screening for delirium in the emergency department: a systematic review. Ann Emerg Med 63:551 Eme, e552
Lee SH, Chan RC, Wu JY et al (2013) Diagnostic value of procalcitonin for bacterial infection in elderly patients – a systemic review and meta-analysis. Int J Clin Pract 67:1350–1357
Lipowski ZJ (1992) Update on delirium. Psychiatr Clin North Am 15:335–346
Man Sy, Lee N, Ip M et al (2007) Prospective comparison of three predictive rules for assessing severity of community-acquired pneumonia in Hong Kong. Thorax 62:348–353
Marengoni A, Von Strauss E, Rizzuto D et al (2009) The impact of chronic multimorbidity and disability on functional decline and survival in elderly persons. A community-based, longitudinal study. J Intern Med 265:288–295
Meurer WJ, Smith BL, Losman ED et al (2009) Real-time identification of serious infection in geriatric patients using clinical information system surveillance. J Am Geriatr Soc 57:40–45
Mody L, Juthani-Mehta M (2014) Urinary tract infections in older women: a clinical review. JAMA 311:844–854
Monette J, Galbaud DU, Fort G, Fung SH et al (2001) Evaluation of the Confusion Assessment Method (CAM) as a screening tool for delirium in the emergency room. Gen Hosp Psychiatry 23:20–25
Nasa P, Juneja D, Singh O et al (2012) Severe sepsis and its impact on outcome in elderly and very elderly patients admitted in intensive care unit. J Intensive Care Med 27:179–183
Nemec M, Koller MT, Nickel CH et al (2010) Patients presenting to the emergency department with non-specific complaints: the Basel Non-specific Complaints (BANC) study. Acad Emerg Med 17:284–292
Norman DC (2000) Fever in the elderly. Clin Infect Dis 31:148–151
Parker LJ, Vukov LF, Wollan PC (1997) Emergency department evaluation of geriatric patients with acute cholecystitis. Acad Emerg Med 4:51–55
Platts-Mills TF, Travers D, Biese K et al (2010) Accuracy of the emergency severity index triage instrument for identifying elder emergency department patients receiving an immediate life-saving intervention. Acad Emerg Med 17:238–243
Riquelme R, Torres A, El-Ebiary M et al (1997) Community-acquired pneumonia in the elderly. Clinical and nutritional aspects. Am J Respir Crit Care Med 156:1908–1914
Ruedinger JM, Nickel CH, Maile S et al (2012) Diuretic use, RAAS blockade and morbidity in elderly patients presenting to the Emergency Department with non-specific complaints. Swiss Med Wkly 142:w13568
Samaras N, Chevalley T, Samaras D et al (2010) Older patients in the emergency department: a review. Ann Emerg Med 56:261–269
Simonetti AF, Viasus D, Garcia-Vidal C et al (2014) Management of community-acquired pneumonia in older adults. Ther Adv Infect Dis 2:3–16
Singler K, Bertsch T, Heppner HJ et al (2013) Diagnostic accuracy of three different methods of temperature measurement in acutely ill geriatric patients. Age Ageing 42:740–746
Singler K, Christ M, Sieber C et al (2011) [Geriatric patients in emergency and intensive care medicine]. Internist (Berl) 52:934–938
Singler K, Thiem U, Christ M et al (2014) Aspects and assessment of delirium in old age: First data from a German interdisciplinary emergency department. Z Gerontol Geriatr 47:680–685
Wagenlehner FM, Schmiemann G, Hoyme U et al (2011) [National S3 guideline on uncomplicated urinary tract infection: recommendations for treatment and management of uncomplicated community-acquired bacterial urinary tract infections in adult patients]. Urologe A 50:153–169
Wong CL, Holroyd-Leduc J, Simel DL et al (2010) Does this patient have delirium?: value of bedside instruments. JAMA 304:779–786
Young J, Meagher D, Maclullich A (2011) Cognitive assessment of older people. BMJ 343:d5042
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M. Hortmann, K. Singler, F. Geier und M. Christ geben an, dass kein Interessenkonflikt besteht.
Dieser Beitrag beinhaltet keine Studien an Menschen oder Tieren.
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Hortmann, M., Singler, K., Geier, F. et al. Erkennen von Infektionen beim älteren Notfallpatienten. Z Gerontol Geriat 48, 601–607 (2015). https://doi.org/10.1007/s00391-015-0903-2
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DOI: https://doi.org/10.1007/s00391-015-0903-2