Skip to main content
Log in

Dementia among older in-hospital patients with obstructive airway disease

Frequency and consequences

Demenz bei älteren Klinikpatienten mit obstruktiver Ventilationsstörung

Häufigkeit und Folgen

  • Original Contribution
  • Published:
Zeitschrift für Gerontologie und Geriatrie Aims and scope Submit manuscript

Abstract

Background

Dementia may influence as a co-morbid condition the management of chronic obstructive airway disease. However, the frequency and the consequences of dementia in older people with chronic obstructive airway disease are largely unknown.

Patients and methods

The frequency and the severity of dementia in geriatric in-hospital patients and its impact on feasibility of lung function testing and drug treatment provided were determined.

Results

Out of a total of 1,424 patients with obstructive airway disease, 433 (30%) suffered from mild and 307 (22%) suffered from moderate to severe dementia. The frequency of any treatment for obstructive airway disease on admission decreased from 58% in subjects without dementia to 51% of those with mild and to 36% of those with moderate to severe dementia (p<0.01). The feasibility of performing lung function testing also decreased with increasing prevalence of dementia from 86% to 66% and 43%, respectively (p<0.001).

Conclusion

Dementia is a frequent finding in older in-hospital patients with obstructive airway disease. The majority of subjects with dementia were not able to perform lung function testing. Furthermore, the risk of undertreatment for chronic obstructive airway disease increased. Future guidelines for management of obstructive airway disease must also take into account the special needs and skills of older subjects with dementia.

Zusammenfassung

Hintergrund

Eine Demenzerkrankung kann das Management einer obstruktiven Ventilationsstörung beeinflussen. Die Häufigkeit und Folgen einer Demenz bei Patienten mit obstruktiver Ventilationsstörung sind aber nicht bekannt.

Patienten und Methoden

Bestimmt wurden die Häufigkeit und der Schweregrad einer Demenzerkrankung sowie deren Auswirkung auf die Durchführbarkeit einer Lungenfunktionstestung und die medikamentöse Therapie bei geriatrischen Klinikpatienten mit obstruktiver Ventilationsstörung.

Ergebnisse

Von 1424 Patienten mit obstruktiver Ventilationsstörung hatten 433 (30%) ein mildes und 307 (22%) Patienten ein moderates bis schweres Demenzsyndrom. Zum Zeitpunkt der Klinikaufnahme erhielten 58% der Patienten ohne Demenz, 51% derjenigen mit milder Demenz und 36% derjenigen mit moderater bis schwerer Dement eine medikamentöse Behandlung ihrer obstruktiven Ventilationsstörung (p<0,01). Die Durchführbarkeit einer Lungenfunktionsprüfung sank mit Vorliegen und Schwere einer Demenz von 86% auf 66% bzw. 43% (p<0,001).

Schlussfolgerung

Viele ältere Klinikpatienten mit obstruktiver Ventilationsstörung haben gleichzeitig ein Demenzsyndrom. Bei Vorliegen einer Demenz sinkt die Wahrscheinlichkeit für eine Therapie der obstruktiven Ventilationsstörung und die Durchführbarkeit einer Lungenfunktionsprüfung. Zukünftige Leitlinien zur Behandlung einer obstruktiven Ventilationsstörung müssen auch die speziellen Bedürfnisse und Fähigkeiten Demenzkranker berücksichtigen.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Allen SC (2003) Spirometry in old age. Age Ageing 32:4–5

    Article  PubMed  Google Scholar 

  2. Antonelli Incalzi R, Marra C, Giordano A et al (2003) Cognitive impairment in chronic obstructive pulmonary disease – a neuropsychological and spect study. J Neurol 250:325–332

    Article  Google Scholar 

  3. Auer S, Reisberg B (1997) The GDS/FAST staging system. Int Psychogeritatr 9 (S1):167–171

    Article  Google Scholar 

  4. Bellia B, Pistelli R, Catalano F et al (2000) Quality control of spirometry in the elderly – the Sara study. Am J Respir Crit Care Med 161:1094–1100

    PubMed  CAS  Google Scholar 

  5. Braak H, Braak E (1997) Frequency of stages of Alzheimer-related lesions in different age categories. Neurobiol Aging 18:351–357

    Article  PubMed  CAS  Google Scholar 

  6. Buist AS, McBurnie MA, Vollmer WM et al (2007) International variation in the prevalence of COPD (the BOLD study): a population-based prevalence study. Lancet 370:741–750

    Article  PubMed  Google Scholar 

  7. Carvahaes-Neto N, Lorino H, Gallinari C et al (1995) Cognitive function and assessment of lung function in the elderly. Am J Respir Crit Care Med 152:1611–1615

    Google Scholar 

  8. Cydulkla RK, McFadden ER, Emerman CL et al (1999) Patterns of hospitalization in elderly patients with asthma and chronic obstructive pulmonary disease. Am J Respir Crit Care Med 156:1807–1812

    Google Scholar 

  9. Dodd JW, Getov SV, Jones PV (2010) Cognitive function in COPD. Eur Respir J 35:913–922

    Article  PubMed  CAS  Google Scholar 

  10. Einer MD, Blanc PD, Yelin EH et al (2008) COPD as a systemic disease: impact on physical functional limitations. Am J Med 121:789–796

    Article  Google Scholar 

  11. Folstein MF, Folstein SE, McHugh PR (1975) Mini-mental-state: a practical method for grading the cognitive state of patients for clinicians. J Am Soc Psych Res 12:189–198

    CAS  Google Scholar 

  12. Formiga F, Fort I, Robles MJ et al (2007) Medical comorbidity in elderly patients with dementia. Differences according to age and gender. Rev Clin Esp 207(10):495–500

    Article  PubMed  CAS  Google Scholar 

  13. Frohnhofen H, Hagen O (2011) Handgrip strength measurement as a predictor for successful dry powder inhaler treatment. Application in older individuals with COPD. Z Gerontol Geriatr in press

  14. Global strategy for the diagnosis, management and prevention of chronic obstructive pulmonary disease 2009. Global initiative for chronic obstructive lung disease (GOLD). http://www.goldcopd.org. Accessed 04 July 2011

  15. Gonneratne N, Patel NP, Corcoran A (2010) Chronic obstructive pulmonary disease and management in older adults. J Am Ger Soc 58:1153–1162

    Article  Google Scholar 

  16. Hung WW, Wisnivesky JP, Siu AL, Ross JS (2009) Cognitive decline among patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 180:134–137

    Article  PubMed  Google Scholar 

  17. Incalzi RA, Gemma A, Marra C et al (1993) Chronic obstructive pulmonary disease. An original model of cognitive decline. Am Rev Respir Dis 148:418–424

    PubMed  CAS  Google Scholar 

  18. Isoaho R, Puolijoki H, Huhti E et al (1996) Chronic obstructive pulmonary disease and cognitive impairment in the elderly. Int Psychogeriatr 8:113–125

    Article  PubMed  CAS  Google Scholar 

  19. Kleerup E (2007) Quality indicators for the care of chronic obstructive pulmonary disease in vulnerable elders. J Am Ger Soc 55:S270–S276

    Article  Google Scholar 

  20. Mahoney F, Barthel D (1965) Functional evaluation: the Barthel Index. Md State Med J 14:56–61

    Google Scholar 

  21. McKhann G, Drachmann D, Folstein M et al (1984) Clinical diagnosis of Alzheimer’s disease. Neurology 34:939–944

    PubMed  CAS  Google Scholar 

  22. Reisberg B, Ferris SH, Leon MJ de, Crook T (1982) The global deterioration scale for assessment of primary degenerative dementia. Am J Psychiatry 139:1136–1139

    PubMed  CAS  Google Scholar 

  23. Rezzoli L, Giardini G, Consonni S et al (2003) Quality of spirometric performance in older people. Age Ageing 32:43–46

    Article  Google Scholar 

  24. Valente S, Pasciuto G, Bernabei R, Corbo GM (2010) Do we need different treatments for very elderly COPD patients? Respiration 80:357–368

    Article  PubMed  CAS  Google Scholar 

Download references

Conflict of interest

The corresponding author states that there are no conflicts of interest.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to H. Frohnhofen.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Frohnhofen, H., Heuer, H., Willschrei, H. et al. Dementia among older in-hospital patients with obstructive airway disease. Z Gerontol Geriat 44, 240–244 (2011). https://doi.org/10.1007/s00391-011-0223-0

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00391-011-0223-0

Keywords

Schlüsselwörter

Navigation