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Effect of triclosan-coated sutures on surgical site infections in pilonidal disease: prospective randomized study

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International Journal of Colorectal Disease Aims and scope Submit manuscript

Abstract

Purpose

The aim of this study is to investigate the effect of triclosan-coated sutures on surgical site infections after wide excision and primary closure for pilonidal disease.

Methods

One hundred seventy-seven patients were randomized into two groups: 91 in control and 86 in triclosan groups. In the control group, 1/0 monofilament polypropylene retention sutures, 3/0 polyglactin subcutaneous sutures, and 3/0 polypropylene skin sutures were used. In the triclosan group, 1/0 triclosan-coated monofilament polydioxanone, 3/0 triclosan-coated polyglactin, and 3/0 triclosan-coated monofilament polydioxanone were used. Postoperative care and follow-up was made by a surgeon according to Centers for Disease Control guideline. Surgical site infection rates between groups were compared. Secondary outcomes were seroma and wound dehiscence.

Results

Seroma was seen in 30 (16.9%) patients: 20 (23.3%) in the triclosan group and 10 (10.9%) in the control group (p = 0.030). Thirteen (7.3%) patients had superficial wound dehiscence: 5 (5.5%) patients in the control group and 10 (11.6%) patients in the triclosan group (p = 0.116). Overall surgical site infection (SSI) rate was 15.8% (n = 28): 19 (20.8%) patients in the control group and 9 (10.5%) patients in the triclosan group (p = 0.044). Healing was observed on mean 17.8 ± 6.7 days. Primary and secondary healing rates and time to healing were similar between groups.

Conclusion

Triclosan-coated sutures decreased surgical site infection rate but had no effect on time to healing in pilonidal disease. Seroma and wound dehiscence were more common in triclosan groups. Randomized trials are needed to clear the effect of triclosan-coated sutures on postoperative wound complications.

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Author information

Authors and Affiliations

  1. Department of General Surgery, Medipol University, Birlik mah Bahceler cd 5, 34230, Istanbul, Turkey

    Naciye Cigdem Arslan

  2. Department of General Surgery, Gokceada State Hospital, 17760, Canakkale, Turkey

    Gulsen Atasoy

  3. Department of General Surgery, Kanuni SS Research Hospital, 34303, Istanbul, Turkey

    Tansu Altintas

  4. Department General Surgery, Bogazici Academy of Clinical Sciences, 34357, Istanbul, Turkey

    Cem Terzi

Authors
  1. Naciye Cigdem Arslan
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  2. Gulsen Atasoy
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  3. Tansu Altintas
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  4. Cem Terzi
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Corresponding author

Correspondence to Naciye Cigdem Arslan.

Ethics declarations

The study was approved by Dokuz Eylul University Ethics Committee (approval no. 20101193-17). The patients were detailly informed about the protocol and written consent was received.

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Arslan, N.C., Atasoy, G., Altintas, T. et al. Effect of triclosan-coated sutures on surgical site infections in pilonidal disease: prospective randomized study. Int J Colorectal Dis 33, 1445–1452 (2018). https://doi.org/10.1007/s00384-018-3138-z

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  • DOI: https://doi.org/10.1007/s00384-018-3138-z

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