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The relation between quality of life and histopathology in diverticulitis; can we predict specimen-related outcome?

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International Journal of Colorectal Disease Aims and scope Submit manuscript

Abstract

Purpose

An important factor in the decision to perform laparoscopic sigmoid resection for patient suffering from recurrent and ongoing diverticulitis is quality of life (QoL). It is unknown whether quality of life relates to the severity of diverticulitis as seen in the resected colonic segment. The aim of this study is to analyze histopathological findings of patients suffering from recurrent or ongoing diverticulitis and their QoL before and after surgery in order to improve patient outcome prediction.

Methods

A cohort of consecutive patients with diverticulitis between January 2010 and April 2014 was analyzed. All patients were scheduled for surgery and had at least three episodes of diverticulitis or more within the last 2 years or experienced ongoing complaints for at least 3 months or more and confirmation by a radiologist. We compared QoL questionnaires, to known histopathological entities.

Results

For this study, 54 consecutive patients were included, 15 (27.8 %) men and 39 (72.2 %) women. A marked difference in quality of life before and after surgery for patients having a more severe histopathological entity was not found (p = 0.83). However, a clinically relevant higher VAS score 6 months after surgery was shown in patients with peritonitis. Furthermore, these patients had more fibrosis in the histopathological samples.

Conclusion

In conclusion, even though a relation between the different pathological entities and QoL could not be determined, patients with diverticulitis and concomitant microscopic peritonitis had significantly more fibrosis and suffered from a higher VAS scores 6 months after surgery.

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Acknowledgments

The authors thank the patients involved in this research.

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Authors and Affiliations

  1. Department of Surgery, Meander Medical Centre, PO box 1502, 3800 BM, Amersfoort, The Netherlands

    M. A. W. Stam, E. C. J. Consten, I. A. M. J. Broeders & W. A. Draaisma

  2. Department of Pathology, Meander Medical Centre, PO box 1502, 3800 BM, Amersfoort, The Netherlands

    L. Arensman

  3. div. Julius Center, Biostatistics, UMC Utrecht, Huispost Str 6.131, Postbus 85500, 3508 GA, Utrecht, The Netherlands

    R. K. Stellato

Authors
  1. M. A. W. Stam
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  2. L. Arensman
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  3. R. K. Stellato
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  4. E. C. J. Consten
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  5. I. A. M. J. Broeders
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  6. W. A. Draaisma
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Correspondence to M. A. W. Stam.

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Stam, M.A.W., Arensman, L., Stellato, R.K. et al. The relation between quality of life and histopathology in diverticulitis; can we predict specimen-related outcome?. Int J Colorectal Dis 30, 665–671 (2015). https://doi.org/10.1007/s00384-015-2176-z

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  • DOI: https://doi.org/10.1007/s00384-015-2176-z

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