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International Journal of Colorectal Disease

, Volume 24, Issue 3, pp 355–356 | Cite as

Leptomeninges as the first and only dissemination site of colorectal cancer

  • Marija Crncevic-UrekEmail author
  • Tomislav Bokun
  • Milan Kujundzic
  • Marko Banic
  • Tajana Stoos-Veic
  • Ivica Grgurevic
  • Mirna Korica
Letter to the Editor

Dear Editor,

Colorectal cancer (CRC) is one of the most common cancer types in the world, ranked second in developed countries for both genders, with the incidence of around 70–80 per population of 100,000. CRC disseminates most frequently to liver, lung, and bones, whereas it is rather rare in other organs. The incidence of colorectal adenocarcinoma dissemination to the leptomeninges is not estimated and seems to be quite rare. We report a case of a woman with CRC and the disease dissemination to the leptomeninges as the first and only dissemination site.

A 61-year-old woman presented to the infectious diseases emergency room with a one-month history of fatigue, fever, photophobia, and mild headache that progressed to severe headache and vertigo. All of these symptoms appeared shortly after a mild conjunctivitis on both eyes that was treated with tobramycin eye-drops. The patient also emphasized a 1-year history of strabismus of the right eye and substantial weight loss of about 12 kg...

Keywords

Colorectal Adenocarcinoma Maxillary Sinusitis Pathological Substrate Leptomeningeal Carcinomatosis Convergent Strabismus 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Copyright information

© Springer-Verlag 2008

Authors and Affiliations

  • Marija Crncevic-Urek
    • 1
    Email author
  • Tomislav Bokun
    • 1
  • Milan Kujundzic
    • 1
  • Marko Banic
    • 1
  • Tajana Stoos-Veic
    • 2
  • Ivica Grgurevic
    • 1
  • Mirna Korica
    • 1
  1. 1.Department of Medicine, Division of Gastroenterology and HepatologyUniversity Hospital DubravaZagrebCroatia
  2. 2.Department of CytologyUniversity Hospital DubravaZagrebCroatia

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