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Analysis of rectal dynamic and static compliances in patients with irritable bowel syndrome

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International Journal of Colorectal Disease Aims and scope Submit manuscript

Abstract

Aims

Our aim was to investigate whether the dynamic and static compliances differ between patients with irritable bowel syndrome (IBS) and normal subjects.

Materials and methods

Fifty-five IBS patients (age range 20–65 years, mean age 39.0 years, 28 women and 27 men; 36 diarrhea-predominant IBS (IBS-D) patients and 19 constipation-predominant IBS (IBS-C) patients) with symptoms that fulfilled the Rome-II criteria and 21 healthy controls (age range 25–58 years, mean age 37.8 years; 11 women and ten men) were recruited. The anorectal functions, including dynamic compliance, were evaluated via barostat tests. A power exponential model was used for the evaluation of static compliance.

Results

There was no significant difference in dynamic compliance between the normal subjects and the IBS patients (10.3 ± 3.1 and 8.9 ± 2.9 mmHg, respectively, P > 0.05). However, even though no significant difference was detected in the overall shape of the curve (β; P > 0.05), there were significant differences in the κ and P half between the normal subjects and the IBS patients (P < 0.05), respectively. When we compared the dynamic and static compliances between the IBS-C and IBS-D patients, there were no significant differences found (P > 0.05).

Conclusions

An exponential model provided good fit to the actual data, and there were significant differences in static compliance between the normal subjects and the IBS patients. This result can reveal the altered biomechanical properties of the gut wall in IBS patients.

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Authors and Affiliations

  1. Department of Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, South Korea

    Jung Ho Park, Yoo Hum Baek, Dong I. L. Park, Hong Joo Kim, Yong Kyun Cho, Chong I. L. Sohn, Woo Kyu Jeon & Byung Ik Kim

  2. Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea

    Poong-Lyul Rhee

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  1. Jung Ho Park
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  2. Yoo Hum Baek
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  3. Dong I. L. Park
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Correspondence to Jung Ho Park.

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Park, J.H., Baek, Y.H., Park, D.I.L. et al. Analysis of rectal dynamic and static compliances in patients with irritable bowel syndrome. Int J Colorectal Dis 23, 659–664 (2008). https://doi.org/10.1007/s00384-008-0469-1

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  • DOI: https://doi.org/10.1007/s00384-008-0469-1

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