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Meta-analysis of short-term outcomes after laparoscopic resection for rectal cancer

International Journal of Colorectal Disease volume 21, pages 652–656 (2006)Cite this article

Abstract

Background

Laparoscopic resection (LR) has become increasingly popular for the management of rectal cancer. Despite a decade of experience, the safety and efficacy of LR for rectal cancer remains to be established. This report performs a meta-analysis to compare LR with conventional open resection (CR) in patients with rectal cancer.

Methods

Using a defined search strategy, studies directly comparing CR with LR for rectal cancer were identified. The data for patients with rectal cancer treated with both approaches were extracted and used in our meta-analysis. Open surgery and laparoscopic surgery were compared in terms of postoperative mortality, morbidity, complications, oncological clearance, operating time, and time before recovery to a normal diet.

Results

Compared with CR, LR is associated with lower morbidity rates [OR 0.63 (0.41, 1.96) P=0.03], longer operating times [weighted mean difference 1.59 (1.20, 1.98) P<0.00001], similar mortality rates, wound healing disorder rates, urinary disorder rates, cardiopulmony disease rates, all leakage rates, all abscess rates and a positive rate of margin.

Conclusion

LR is associated with less postoperative morbidity, but longer operation time. A prospective randomized controlled trial is warranted to fully investigate these and other outcome measures.

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Affiliations

  1. Department of Coloproctological Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, Guangxi Zhuang Autonomous Region, China

    Feng Gao, Yun-Fei Cao & Li-Sheng Chen

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  1. Feng Gao
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  2. Yun-Fei Cao
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  3. Li-Sheng Chen
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Correspondence to Li-Sheng Chen.

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Gao, F., Cao, YF. & Chen, LS. Meta-analysis of short-term outcomes after laparoscopic resection for rectal cancer. Int J Colorectal Dis 21, 652–656 (2006). https://doi.org/10.1007/s00384-005-0079-0

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  • DOI: https://doi.org/10.1007/s00384-005-0079-0

Keywords

  • Laparoscopic resection
  • Open resection
  • Meta-analysis
  • Rectal cancer