Abstract
Background
Muscle relaxation is administered to patients undergoing laparotomy for colonic surgery. At the end of the procedure, relaxation needs to be reversed to facilitate extubation. This may be achieved by administering anticholinesterases such as neostigmine.
Patient presentation
We present a case of colonic anastomotic dehiscence in the immediate postoperative period following the use of neostigmine to reverse intra-operative muscle relaxation.
Conclusion
Neostigmine is frequently used to reverse muscle relaxation at the end of colonic surgery. However, the drug should be used with caution as it has been implicated as a cause of early anastomotic disruption.
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References
Kreis ME, Kasparek M, Zittel TT, Becker HD, Jehle EC (2001) Neostigmine increases postoperative colonic motility in patients undergoing colorectal surgery. Surgery 130:449–456
Carlstedt A, Nordgren S, Fasth S, Applegren L, Hulten L (1989) Epidural anaesthesia and postoperative colorectal motility—possible hazard to a colorectal anastomosis. Int J Colorect Dis 4:144–149
Bell CM, Lewis CB (1968) Effects of neostigmine on integrity of ileorectal anastomosis. Br Med J 3:587–588
Garcia-Olmo DC, Garcia-Rivas M, Garcia-Olmo D (1998) Does neostigmine have a deleterious effect on the resistance of colonic anastomoses? Eur J Anaesthiol 15:38–43
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Hirst, G.R., Karandikar, S.S., Brown, G. et al. Colonic anastomotic disruption in the immediate postoperative period. Int J Colorectal Dis 19, 281–282 (2004). https://doi.org/10.1007/s00384-003-0564-2
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DOI: https://doi.org/10.1007/s00384-003-0564-2