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Gene therapy in the treatment of intestinal inflammation

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International Journal of Colorectal Disease Aims and scope Submit manuscript

Abstract

Background

Local expression of anti-inflammatory or immunoregulatory genes may offer an alternative treatment of gastrointestinal inflammation.

Discussion

We review the basic requirements for gene therapy, the possible routes of delivery, and the different strategies for specific targeting focusing on gastrointestinal inflammation.

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Authors and Affiliations

  1. Department of Experimental Internal Medicine, Academic Medical Center, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands

    Catherine van Montfrans, Anje A. te Velde, Sander J. H. van Deventer & Maria Sol Rodriguez Pena

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  1. Catherine van Montfrans
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  2. Anje A. te Velde
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  3. Sander J. H. van Deventer
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  4. Maria Sol Rodriguez Pena
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Correspondence to Maria Sol Rodriguez Pena.

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van Montfrans, C., te Velde, A.A., van Deventer, S.J.H. et al. Gene therapy in the treatment of intestinal inflammation. Int J Colorectal Dis 19, 79–86 (2004). https://doi.org/10.1007/s00384-003-0501-4

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