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Post-discharge follow-up of congenital duodenal obstruction patients: a systematic review

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Abstract

Purpose

Long-term follow-up of congenital duodenal obstruction patients often falls on care providers with little experience of this condition. We performed a systematic review of the long-term outcomes of duodenal obstruction and provide a summary of sequelae care providers should anticipate.

Methods

In 2022, after registering with PROSPERA, Medline (Ovid), EMBASE, PSYCHINFO, CNAHL and SCOPUS databases were searched using the title keyword ‘intestinal atresia’. Abstracts were filtered for inclusion if they included the duodenum. Papers of filtered abstracts were included if they reported post-discharge outcomes. Methodological Index for Non-Randomized Studies was used to grade the papers.

Results

Of the 1068 abstracts were screened, 32 papers were reviewed. Eleven studies were included. Thirty additional papers were included after reviewing references, for a total of 41 papers. The average MINORS was 7/16.

Conclusion

There is good evidence that children with congenital duodenal obstruction do well in terms of survival, growth and general well-being. Associated cardiac, musculoskeletal and renal anomalies should be ruled-out. Care providers should be aware of anastomotic dysfunction, blind loop syndrome, bowel obstruction and reflux. Reflux may be asymptomatic. Laparoscopic repair does not change long-term outcomes, and associated Trisomy 21 worsens neurodevelopmental outcomes.

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Funding

Thorlakson Chair in Surgical Research.

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Authors and Affiliations

  1. Department of Surgery, Division of Pediatric Surgery and Children’s Hospital Research Institute of Manitoba, University of Manitoba, AE402-820 Sherbrook Street, Winnipeg, MB, R3A 1S1, Canada

    Suyin A. Lum Min, Malaz Imam, Anna Zrinyi, Anna C. Shawyer & Richard Keijzer

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  1. Suyin A. Lum Min
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  2. Malaz Imam
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SLM, MI and AZ reviewed the literature and gathered the data for the manuscript and wrote the main manuscript text AS helped with the literature review All authors critically reviewed the manuscript.

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Correspondence to Richard Keijzer.

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Lum Min, S.A., Imam, M., Zrinyi, A. et al. Post-discharge follow-up of congenital duodenal obstruction patients: a systematic review. Pediatr Surg Int 39, 239 (2023). https://doi.org/10.1007/s00383-023-05515-w

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