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The effects of tobacco consumption on paternity rates of adults with a history of cryptorchidism

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Abstract

Objective

To determine the effect of tobacco consumption on paternity rates in men with a history of cryptorchidism. To compare the paternity rates between formerly unilateral, bilateral cryptorchid smokers, and nonsmokers.

Methods

A retrospective cohort study of 153 men who had undergone orchiopexy between 1961 and 1985 at the Miguel Servet University Hospital (116 unilateral and 37 bilateral) and a control group of 100 men were evaluated by review of medical records and a questionnaire.

Results

A total of 197 men filled the questionnaire (76.7%). There was no difference in paternity rates between smokers compared to nonsmokers (P = 0.21). In the unilateral cryptorchid men (ULC) group, there is no difference in paternity rates when compared with the controls (P = 0.079) or when comparing ULC smokers to ULC nonsmokers (P = 0.35). In the bilateral cryptorchid men (BLC) group, there is no difference in paternity rates when compared to controls (P = 0.075) or when comparing BLC smokers to BLC nonsmokers (P = 0.36). When comparing according to consumption, there is no difference between mild, moderate or heavy smoker cases and controls.

Conclusion

There is no difference in paternity rates between men with a history of cryptorchidism that consume tobacco compared to nonsmokers or controls. More studies are needed to determine the impact of tobacco consumption in formerly cryptorchid men.

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Author information

Authors and Affiliations

  1. Hospital Universitario Miguel Servet, Zaragoza, Spain

    Rafael Fernández Atuan & Paolo Bragagnini Rodríguez

  2. Hospital Universitari Son Espases, Palma, Spain

    Elena Calleja Aguayo & Blanca Estors Sastre

  3. Consorcio Corporación Sanitaria Parc Tauli, Sabadell, Spain

    Natalia Álvarez García

  4. Hospital Sant Joan de Deu, Esplugues de Llobregat, Spain

    Alexander Siles Hinojosa

  5. Clínica HLA Montpellier Zaragoza, Zaragoza, Spain

    Jesus Gracia Romero

Authors
  1. Rafael Fernández Atuan
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  2. Elena Calleja Aguayo
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  3. Blanca Estors Sastre
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  4. Natalia Álvarez García
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  5. Alexander Siles Hinojosa
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  6. Paolo Bragagnini Rodríguez
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  7. Jesus Gracia Romero
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Contributions

All the authors contributed to the study conception and design. Material preparation and data collection were performed by Dr. RF, Dr. EC and Dr. BE. Analysis was performed by Dr. NÁ, Dr. ASH and Dr. PB. The first draft of the manuscript was written by Dr. RF and all the authors commented on previous versions of the manuscript. All the authors read and approved the final manuscript. The study was supervised by Dr. JG.

Corresponding author

Correspondence to Rafael Fernández Atuan.

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Conflict of interest

The authors declare they have no conflicts of interest.

Research involving human participants

This retrospective study was approved by the Aragonese Institute of Health Sciences and approved by the ethical committee for research of the autonomous community of Aragon (CEICA) N°CP12/2014.

Informed consent

Informed consent was obtained from all individual participants included in the study.

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Fernández Atuan, R., Calleja Aguayo, E., Estors Sastre, B. et al. The effects of tobacco consumption on paternity rates of adults with a history of cryptorchidism. Pediatr Surg Int 36, 241–246 (2020). https://doi.org/10.1007/s00383-019-04598-8

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  • DOI: https://doi.org/10.1007/s00383-019-04598-8

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