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Adenocarcinoma arising from tubulovillous adenoma in a native bladder following gastrocystoplasty

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Abstract

Gastrocystoplasty is a surgical form of bladder augmentation which improves bladder capacity and compliance. Patients who undergo bladder augmentation with a gastric remnant are at increased risk for malignancy. The most common types of tumors in this situation were adenocarcinoma and urothelial carcinoma. Most of the adenocarcinomas arise in the gastric remnant or anastomotic site, and adenocarcinomas arising in the residual native bladder are extremely rare. We report on a patient who received gastrocystoplasty 16 years ago. She suffered from recurrent urinary tract infections for a year and cystoscopy showed a tumor in the bladder trigone. Pathologic examination showed tubulovillous adenoma with malignant transformation to adenocarcinoma. The tumor consisted of intact adenomatous architecture from low-grade dysplastic gland to adenocarcinoma, which suggested that the pathogenesis might be related to intestinal metaplasia and dysplasia. The unique location and immunohistologic findings of the tumor suggested that it originated in the bladder mucosa.

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References

  1. Mingin GC, Stock JA, Hanna MK (1999) Gastrocystoplasty: long-term complications in 22 patients. J Urol 162(3 Pt 2):1122–1125

    CAS  PubMed  Google Scholar 

  2. Husmann DA (2009) Malignancy after gastrointestinal augmentation in childhood. Ther Adv Urol 1(1):5–11

    Article  PubMed Central  PubMed  Google Scholar 

  3. Castellan M, Gosalbez R, Perez-Brayfield M et al (2007) Tumor in bladder reservoir after gastrocystoplasty. J Urol 178(4 Pt 2):1771–1774

    Article  PubMed  Google Scholar 

  4. Balachandra B, Swanson PE, Upton MP et al (2007) Adenocarcinoma arising in a gastrocystoplasty. J Clin Pathol 60(1):85–87

    Article  CAS  PubMed  Google Scholar 

  5. Zhang X, Gupta R, Nicastri AD (2010) Bladder adenocarcinoma following gastrocystoplasty. J Pediatr Urol 6(5):525–527

    Article  PubMed  Google Scholar 

  6. Smith AK, Hansel DE, Jones JS (2008) Role of cystitis cystica et glandularis and intestinal metaplasia in development of bladder carcinoma. Urology 71(5):915–918

    Article  PubMed  Google Scholar 

  7. Austin JC (2008) Long-term risks of bladder augmentation in pediatric patients. Curr Opin Urol 18(4):408–412

    Article  PubMed  Google Scholar 

  8. Vemulakonda VM, Lendvay TS, Shnorhavorian M et al (2008) Metastatic adenocarcinoma after augmentation gastrocystoplasty. J Urol 179(3):1094–1096

    Article  PubMed  Google Scholar 

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Acknowledgments

The authors thank all the staff of the Department of Urology of Mackay Memorial Hospital for their assistance.

Conflict of interest

There was no conflict of interest in this study.

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Authors and Affiliations

  1. Department of Urology, Mackay Memorial Hospital, Taipei, Taiwan, ROC

    Ting-Po Lin, Marcelo Chen & Jong-Ming Hsu

  2. Department of Pediatric Surgery, Mackay Memorial Hospital, No. 92, Sec. 2, Jhongshan N. Rd., Jhongshan Dist., Taipei, 104, Taiwan, ROC

    J. C. Sheu

Authors
  1. Ting-Po Lin
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  2. Marcelo Chen
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  3. Jong-Ming Hsu
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  4. J. C. Sheu
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Correspondence to J. C. Sheu.

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Lin, TP., Chen, M., Hsu, JM. et al. Adenocarcinoma arising from tubulovillous adenoma in a native bladder following gastrocystoplasty. Pediatr Surg Int 30, 123–126 (2014). https://doi.org/10.1007/s00383-013-3414-5

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  • DOI: https://doi.org/10.1007/s00383-013-3414-5

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