Abstract
The Kasai redo surgery is important for treating biliary atresia. In the era of liver transplantation (LTx), pediatric surgeons must accurately select patients for redo surgery and ensure that potential LTx can be performed later. Although optimal timing for redo varies among cases, appropriate timing is essential. We reviewed the significance, optimal timing, operative procedures, and indications of Kasai redo surgery. Between 1989 and 2011, 2,630 patients were registered in the Japanese Biliary Atresia Registry (JBAR), and the data collected from JBAR regarding Kasai redo surgery were analyzed. Patients were divided into two groups, Group 1 (1989–1999, n = 1,423) and Group 2 (2000–2011, n = 1,207). The redo incidence significantly reduced in Group 2. Although no significant difference was found in the native liver jaundice-free survival rates between the two groups, the overall survival rate at initial registry was significantly higher in Group 2. This may be because of the limited number of patients selected for redo and increased availability of early LTx. Patients who achieved sufficient bile drainage following the initial Kasai surgery but developed sudden bile flow cessation were the best candidates for Kasai redo surgery; it should be performed only once for this subset.
Similar content being viewed by others
References
Meister RK, Esquivel CO, Cox KL et al (1993) The influence of portoenterostomy with stoma on morbidity in pediatric patients with biliary atresia undergoing orthotopic liver transplantation. J Pediatr Surg 28:387–390
National Institutes of Health Consensus Development Conference Statement (1984) Liver transplantation—June 20–23, 1983. Hepatology 4(1 Suppl):107S–110S
Sandler AD, Azarow KS, Superina RA (1997) The impact of a previous Kasai procedure on liver transplantation for biliary atresia. J Pediatr Surg 32:416–419
Wang Q, Yan LN, Zhang MM, Wang WT et al (2013) The pre-Kasai procedure in living donor liver transplantation for children with biliary atresia. Hepatobiliary Pancreat Dis Int 12:47–53
Vacanti JP, Shamberger RC, Eraklis A et al (1990) The therapy of biliary atresia combining the Kasai portoenterostomy with liver transplantation: a single center experience. J Pediatr Surg 25:149–152
Visser BC, Suh I, Hirose S et al (2004) The influence of portoenterostomy on transplantation for biliary atresia. Liver Transpl 10:1279–1286
Bondoc AJ, Taylor JA, Alonso MH et al (2012) The beneficial impact of revision of Kasai portoenterostomy for biliary atresia: an institutional study. Ann Surg 255:570–576
Lilly JR, Karrer FM, Hall RJ et al (1989) The surgery of biliary atresia. Ann Surg 210:289–296
Ito F, Ando H, Seo T et al (1997) Optimal timing for reoperation in the treatment of biliary atresia. Jpn J Pediatr Sug 29:934–938
Ohi R, Hanamatsu M, Mochizuki I et al (1985) Reoperation in patients with biliary atresia. J Pediatr Surg 20:256–259
Nishi T, Yamamoto H, Kashimura T (1997) The results of long-term follow-up after reoperation for biliary atresia, analysis of the timing for reoperation. Jpn J Pediatr Sug 29:928–933
Ando H, Kaneko K, Ono Y et al (2008) Value of reoperation after Kasai portoenterostomy in the times of liver transplantation for biliary atresia. Jpn J Pediatr Sug 40:119–122
Graeve AH, Volpicelli N, Kosloske AM (1982) Endoscopic recanalization of a portoenterostomy. J Pediatr Surg 17:901–903
Okada A, Kubota A, Fukui Y et al (1987) Endoscopic observation and treatment of portahepatis in biliary atresia. In: Ohi R (ed) Biliary atresia. Professional Postgraduate Service, Tokyo, pp 188–193
Ibrahim M, Ohi R, Chiba T et al (1991) Indications and results of reoperation for biliary atresia. In: Ohi R (ed) Biliary atresia. Icom Associates Inc, Tokyo, pp 96–100
Freitas L, Gauthier F, Valayer J (1987) Second operation for repair of biliary atresia. J Pediatr Surg 22:857–860
Sugawara Y, Makuuchi M, Kaneko J et al (2004) Impact of previous multiple portoenterostomies on living donor liver transplantation for biliary atresia. Hepatogastroenterology 51:192–194
Millis JM, Brems JJ, Hiatt JR et al (1988) Orthotopic liver transplantation for biliary atresia. Evolution of management. Arch Surg 123:1237–1239
Wood RP, Langnas AN, Stratta RJ et al (1990) Optimal therapy for patients with biliary atresia: portoenterostomy (“Kasai” procedures) versus primary transplantation. J Pediatr Surg 25:153–162
The Japanese Liver Transplantation Society (2011) Liver Transplantation in Japan, Registry by the Japanese liver transplantation society. Jpn J Transplant 46:524–536
Japanese Society for Biliary Atresia (2013) Japanese biliary atresia registry 2011. J Jpn Soc Pediatr Sug 49:277–289
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Nio, M., Sasaki, H., Tanaka, H. et al. Redo surgery for biliary atresia. Pediatr Surg Int 29, 989–993 (2013). https://doi.org/10.1007/s00383-013-3396-3
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00383-013-3396-3