Abstract
We reviewed our experience over 10 years with pyeloplasty for ureteropelvic junction obstruction. Preoperative and postoperative isotope renal scans were performed to assess the surgical outcome, with particular emphasis on the postoperative change in renal function (RF). We retrospectively reviewed the medical records of 137 consecutive children with ureteropelvic obstruction operated between January 1994 and December 2003. A total of 109 kidneys in 102 patients were evaluated with renal echo and 99mTc-diethylenetriaminepentaacetic renography both before and after Anderson–Hynes dismembered pyeloplasty. The improvement of RF >5% was noted in 67 kidneys (61.5%), the function remained stable in 30 kidneys (27.5%), and it deteriorated (>5%) in 12 kidneys (11.0%). Five patients (4.6%) required repeat pyeloplasty for either prolonged urine leakage or reobstruction with deterioration in RF. Dismembered pyeloplasty in children with ureteropelvic junction obstruction is safe. The renal functional improvement can be expected in the majority of kidneys that have impaired function at presentation.
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Zhang PL, Peters CA, Rosen S (2000) Ureteropelvic junction obstruction: morphological and clinical studies. Pediatr Nephrol 14:820–826
Chiou YY, Chiu NT, Wang ST (2004) Factors associated with the outcomes of children with unilateral ureteropelvic junction obstruction. J Urol 171:397–402
Raviv G, Leibovitch I, Shenfeld O, Mor Y, Jonas P, Goldwasser B (1994) Ureteropelvic junction obstruction: relation of etiology and age at surgical repair to clinical outcome. Urol Int 52:135–139
Di Sandro MJ, Kogan BA (1998) Ureteropelvic junction obstruction (neonatal management-role for early intervention). Urol Clin North Am 25:187–195
Koff SA (1998) Neonatal management of unilateral hydronephrosis: role for delayed intervention. Urol Clin North Am 25:181–186
Tapia J, Gonzalez R (1995) Pyeloplasty improves renal function and somatic growth in children with ureteropelvic junction obstruction. J Urol 154:218–222
Moon DH, Park YS, Jun NL, Lee SY, Kim KS, Yoon CH, Kang W, Lee HK (2003) Value of supranormal function and renogram patterns on 99 m 99mTc-mercaptoacetyltriglycine scintigraphy in relation to the extent of hydronephrosis for predicting ureteropelvic junction obstruction in the newborn. J Nucl Med 44:725–731
Majd M (1992) Nuclear medicine in pediatric urology. In: Kelalis PP King LR, Belman AB (eds) Clinical pediatric urology. W.B. Saunders, Philadelphia, pp 117–165
Anderson JC, Hynes W (1949) Retrocaval ureter: a case diagnosed preoperatively and treated successfully by a plastic operation. Brit J Urol 21:209
Pierre Mouriquand (1998) Congenital anomalies of the pyeloureteral junction and the ureter. In: O’Neil JA, Rowe MI (eds) Pediatric surgery. Mosby-year Book, St Louis, pp 1599–1602
Ransley P (1985) “Extended” role of DTPA scan in assessing function and UPJ obstruction in the neonate. Dialog Pediatr Urol 8:3
Palmer LS, Maizels M, Cartwright PC, Fernbach SK, Conway JJ (1998) Surgery versus observation for managing obstructive grade 3 to 4 unilateral hydronephrosis: a report from the Society for Fetal Urology. J Urol 159:222
Blyth B, Snyder HM, Duckett JW (1993) Antenatal diagnosis and subsequent management of hydronephrosis. J Urol 149:693–698
Fernbach SK, Maizels M, Comway JJ (1993) Ultrasound grading of hydronephrosis: introduction to the system used by the Society for Fetal Urology. Pediatr Radiol 23:478–480
Conway JJ, Maizels M (1992) The “well tempered” diuretic renogram: a standard method to examine the asymptomatic neonate with hydronephrosis or hydroureteronephrosis: a report from combined meetings of the Society for Fetal Urology and members of the Pediatric Nuclear Medicine Council—the Society of Nuclear Medicine. J Nucl Med 33:2047–2051
Salem YH, Majd M, Rushton HG, Belman AB (1995) Outcome analysis of pediatric pyeloplasty as a function of patient age, presentation and differential renal function. J Urol 154:1889–1993
Tapia J, Gonzalez R (1995) Pyeloplasty improves renal function and somatic growth in children with ureteropelvic junction obstruction. J Urol 154:218–222
King RL, Coughlin PW, Bloch EC, Bowie JD, Ansong K, Hanna MK (1984) The case for immediate pyeloplasty in the neonate with ureteropelvic junction obstruction. J Urol 132:725–728
Oreilly PH (1989) Functional outcome of pyeloplasty for ureteropelvic junction obstruction: prospective study in 30 consecutive cases. J Urol 142:273–275
Chung S, Majd M, Rushton HG, Belmann AB (1993) Diuretic renography in the evaluation of neonatal hydronephrosis: is it reliable? J Urol Part 2 150:765–768
Elder JS, Stansbrey R, Dahms BB, Selzman AA (1995) Renal histological changes secondary to ureteropelvic junction obstruction. J Urol 154:719–722
Vaughan ED Jr, Gillenwater JY (1971) Recovery following complete chronic unilateral ureteral occlusion: functional, radiography and pathologic alterations. J Urol 106:27–35
Fink RL, Caridis DT, Chimeil R, Ryan G (1980) Renal impairment and its reversibility following variable periods of complete ureteric obstruction. Aust N Z J Surg 50:77–83
Huguenin ME, Thiel GT, Brunner FP, Torhorst J, Fluckiger EW, Wirz H (1974) Recovery of kidney after release of ureteral occlusion in the rat (author’s transl.) (French). Kidney Int 5:221–232
Mayor G, Genton N, Torrado A, Guignard LP (1975) Renal function in obstructive nephropathy: long-term effect of re-constructive surgery. Pediatrics 56:740–747
Josephson S, Dhillon HK, Ransley PG (1993) Post-natal management of antenatally detected, bilateral hydrocephrosis. Urol Int 51:79–84
Ulman I, Jayanthi VR, Koff SA (2000) The long-term followup of newborns with severe unilateral hydronephrosis initially treated nonoperatively. J Urol 164:1101–1105
Koff SA, Thrall JH, Keyes JW Jr (1979) Diauretic radionuclide urography: a non-invasive method for evaluating nephrouretral dilatation. J Urol 122:451–454
Murakumo M, Nonomura K, Yamashita T, Ushiki T, Abe K, Koyangi T (1997) Structural changes of collagen components and diminution of nerves in congenital ureteropelvic junction obstruction. J Urol 157:1963–1968
Wag Y, Puri P, Hassan J, Mitakita H, Reen DJ (1995) Abnormal innervation and altered nerve growth factor messenger ribonucleic acid expression in ureteropelvic junction obstruction. J Urol 154:679–683
Harish J, Joshi K, Rao KL, Narasimhan KL, Samujh R, Choudhary SK, Mahajan JK (2003) Pelviureteric junction obstruction: how much is the extent of the upper ureter with defective innervation needing resection? J Pediatr Surg 31:1194–1198
Piepsz A, Dobbeleir A, Erbsman F (1977) Measurement of separate kidney clearance by means of 99mTc-DTPA complex and a scintillation camera. Eur J Nucl Med 2:173–177
Vivain G, Gordon I (1983) Comparison between individual kidney GFR estimated at 20 minutes with 99mTc-DTPA + 51 Cr EDTA GFR in children with single kidney. Nucl Med Commun 4:108
Ransley PG, Dhillon HK, Gordon I, Duffy PG, Dillon MJ, Barratt TM (1990) The postnatal management of hydronephrosis diagnosed by prenatal ultrasound. J Urol 144:584–587
Houben CH, Wischermann S, Borner G, Slany E (2000) Outcome analysis of pyeloplasty in infants. Pediatr Surg Int 16:189–193
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Sheu, JC., Koh, CC., Chang, PY. et al. Ureteropelvic junction obstruction in children: 10 years’ experience in one institution. Ped Surgery Int 22, 519–523 (2006). https://doi.org/10.1007/s00383-006-1698-4
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DOI: https://doi.org/10.1007/s00383-006-1698-4