Abstract
We herein report the case of three siblings presenting with intestinal malrotation. Their medical history and circumstances of diagnosis are described. Barium meal demonstrated a minor duodenal anomaly in the mother. As far as we can ascertain, this is the third report of isolated familial malrotation in more than one generation, raising questions about its developmental mechanism. We thus highlight in what circumstances familial investigations should be undertaken in case of malrotation.
This is a preview of subscription content, log in via an institution to check access.
References
Millar AJ, Rode H, Cywes S (2003) Malrotation and volvulus in infancy and childhood. Semin Pediatr Surg 12(4):229–236
Prasil P, Flageole H, Shaw KS, et al (2000) Should malrotation in children be treated differently according to age?. J Pediatr Surg 35(5):756–758
Berrocal T, Lamas M, Guttierez J, et al (1999) Congenital anomalies of the small intestine, colon, and rectum. Radiographics 19:1219–1236
Beaudoin S, Seror O, Fayad F, et al (1999) A case of malrotation and situs ambiguus. Surg Radiol Anat 21:143–145
Kluth D, Kaestner M, Tibboel D, et al (1995) Rotation of the gut: fact or fantasy?. J Pediatr Surg 30:448–453
Kluth D, Jaeschke-Melli S, Fiegel H (2003) The embryology of gut rotation. Semin Pediatr Surg 12 (4):275–279
Crowley JJ, Bawle E (1996) Small bowel malrotation in each pair of identical twin. Pediatr Radiol 26(2):127–128
Erez I, Reish O, Kovalivker M, Lazar L, Raz A, Katz S (2001) Congenital short-bowel and malrotation: clinical presentation and outcome of six affected offspring in three related families. Eur J Pediatr Surg 11(5):331–334
Stalker HJ, Chitayat D (1992) Familial intestinal malrotation with midgut volvulus and facial anomalies: a disorder involving a gene controlling the normal gut rotation?. Am J Hum Gen 44:46–47
Budd JS, Powley PH (1988) Small bowel volvulus in two siblings. Brit Med J 296:1572
Smith SL (1972) Familial midgut volvulus. Surgery 72:420–426
Carmi R, Abeliovich D, Siplovich L, et al (1981) Familial midgut anomalies- a spectrum of defects due to the same cause. Am J Med Genet 8:443–446
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Beaudoin, S., Mathiot-Gavarin, A., Gouizi, G. et al. Familial malrotation: report of three affected siblings. Ped Surgery Int 21, 856–857 (2005). https://doi.org/10.1007/s00383-005-1548-9
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00383-005-1548-9